The coming decade in precision oncology: six riddles

A Wahida, L Buschhorn, S Fröhling, PJ Jost… - Nature Reviews …, 2023 - nature.com
High-throughput methods to investigate tumour omic landscapes have quickly catapulted
cancer specialists into the precision oncology era. The singular lesson of precision oncology …

Epidemiology and genomics of prostate cancer in Asian men

Y Zhu, M Mo, Y Wei, J Wu, J Pan, SJ Freedland… - Nature Reviews …, 2021 - nature.com
Prostate cancer is a global health problem, but incidence varies considerably across
different continents. Asia is traditionally considered a low-incidence area, but the incidence …

Epidemiology of prostate cancer in Asian countries

T Kimura, S Egawa - International journal of urology, 2018 - Wiley Online Library
The incidence of prostate cancer has been increasing worldwide in recent years. The
GLOBOCAN project showed that prostate cancer was the second most frequently diagnosed …

Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches

T Karantanos, PG Corn, TC Thompson - Oncogene, 2013 - nature.com
Prostate cancer is the second-leading cause of cancer-related mortality in men in Western
societies. Androgen receptor (AR) signaling is a critical survival pathway for prostate cancer …

[HTML][HTML] Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

DC Wedge, G Gundem, T Mitchell, DJ Woodcock… - Nature …, 2018 - nature.com
Prostate cancer represents a substantial clinical challenge because it is difficult to predict
outcome and advanced disease is often fatal. We sequenced the whole genomes of 112 …

Prostate cancer treatment–China's perspective

J Liu, L Dong, Y Zhu, B Dong, J Sha, HH Zhu, J Pan… - Cancer letters, 2022 - Elsevier
Prostate cancer (PCa) incidence and mortality have rapidly increased in China. Notably,
unique epidemiological characteristics of PCa are found in the Chinese PCa population …

Whole-genome and transcriptome sequencing of prostate cancer identify new genetic alterations driving disease progression

S Ren, GH Wei, D Liu, L Wang, Y Hou, S Zhu, L Peng… - European urology, 2018 - Elsevier
Background Global disparities in prostate cancer (PCa) incidence highlight the urgent need
to identify genomic abnormalities in prostate tumors in different ethnic populations including …

The TMPRSS2:ERG Rearrangement, ERG Expression, and Prostate Cancer Outcomes: A Cohort Study and Meta-analysis

A Pettersson, RE Graff, SR Bauer, MJ Pitt, RT Lis… - … , biomarkers & prevention, 2012 - AACR
Background: Whether the genomic rearrangement transmembrane protease, serine 2
(TMPRSS2): v-ets erythroblastosis virus E26 oncogene homolog (ERG) has prognostic …

Cancer genomics: diversity and disparity across ethnicity and geography

DSW Tan, TSK Mok, TR Rebbeck - Journal of Clinical Oncology, 2016 - ascopubs.org
Ethnic and geographic differences in cancer incidence, prognosis, and treatment outcomes
can be attributed to diversity in the inherited (germline) and somatic genome. Although …

[HTML][HTML] The incidence, mortality, and risk factors of prostate cancer in Asian men

BH Chung, S Horie, E Chiong - Prostate international, 2019 - Elsevier
The objective of this review was to describe the epidemiology and risk factors of prostate
cancer (PCa) in Asian populations. English language publications published over the last 10 …