A fresh look at reperfusion injury

HM Piper, D Garcña-Dorado… - Cardiovascular research, 1998 - academic.oup.com
In clinical therapy of evolving acute myocardial infarction, coronary reperfusion has proven
to be the only way to limit infarct size, provided it occurs soon enough after coronary artery …

Postconditioning A new link in nature's armor against myocardial ischemia–reperfusion injury

J Vinten-Johansen, ZQ Zhao, AJ Zatta, H Kin… - Basic research in …, 2005 - Springer
Reperfusion injury is a complex process involving several cell types (endothelial cells,
neutrophils, and cardiomyocytes), soluble proinflammatory mediators, oxidants, ionic and …

[HTML][HTML] del Nido versus Buckberg cardioplegia in adult isolated valve surgery

SL Mick, MP Robich, PL Houghtaling… - The Journal of thoracic …, 2015 - Elsevier
Background del Nido solution is a non–glucose-based, single-dose cardioplegic solution
with few data supporting its safety in adults. We hypothesized that it and Buckberg solution …

Advantages of blood cardioplegia over continuous coronary perfusion or intermittent ischemia: experimental and clinical study

DM Follette, DG Mulder, JV Maloney Jr… - The Journal of thoracic …, 1978 - Elsevier
A safe, effective method of producing a quiet, bloodless heart for 2 hours or more has been
developed experimentally and used clinically. Aliquots of oxygenated blood from the …

Update on current techniques of myocardial protection

GD Buckberg - The Annals of thoracic surgery, 1995 - Elsevier
The spectrum of strategies for myocardial protection has led to the artificial creation of
adversarial positions in regard to warm versus cold blood cardioplegia, antegrade versus …

Strategies and logic of cardioplegic delivery to prevent, avoid, and reverse ischemic and reperfusion damage

GD Buckberg - The Journal of thoracic and cardiovascular surgery, 1987 - Elsevier
COld cardioplegic solutions are used almost universally to prevent intraoperative myocardial
ischemic damage during aortic clamping. This review will show that the inclusion of oxygen …

Propensity matched analysis of del Nido cardioplegia in adult coronary artery bypass grafting: initial experience with 100 consecutive patients

T Timek, C Willekes, O Hulme, B Himelhoch… - The Annals of Thoracic …, 2016 - Elsevier
Background Del Nido cardioplegia (DC) offers prolonged cardiac protection with single-
dose administration and has had a long safety record in pediatric cardiac surgery. However …

Benefits of normothermic induction of blood cardioplegia in energy-depleted hearts, with maintenance of arrest by multidose cold blood cardioplegic infusions

ER Rosenkranz, J Vinten-Johansen… - The Journal of thoracic …, 1982 - Elsevier
This study tests the hypothesis that warm induction of cardioplegia prior to prolonged
maintenance by multidose infusions of cold blood cardioplegic solution would increase the …

Safety of prolonged aortic clamping with blood cardioplegia: III. Aspartate enrichment of glutamate-blood cardioplegia in energy-depleted hearts after ischemic and …

ER Rosenkranz, F Okamoto, GD Buckberg… - The Journal of thoracic …, 1986 - Elsevier
This study tests the hypothesis that aspartate enrichment of glutamate-blood cardioplegia
improves metabolic and functional recovery after ischemic and reperfusion damage …

Retrograde coronary sinus perfusion: a safe alternative for ensuring cardioplegic delivery in aortic valve surgery

P Menasche, S Kural, M Fauchet, A Lavergne… - The Annals of thoracic …, 1982 - Elsevier
During aortic valve surgery, cardioplegic solution is delivered through direct cannulation of
both coronary ostia. Since this approach may cause an intimal injury leading to acute …