Porcine circoviruses: current status, knowledge gaps and challenges

T Opriessnig, AK Karuppannan, AMMG Castro… - Virus research, 2020 - Elsevier
Circoviruses (CV) include some of the smallest viruses known. They were named after their
circularly arranged single-stranded DNA genome with a gene encoding a conserved …

Porcine circovirus type 2 (PCV2) vaccines in the context of current molecular epidemiology

AK Karuppannan, T Opriessnig - Viruses, 2017 - mdpi.com
Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and,
although small, it has the highest evolution rate among DNA viruses. Since the discovery of …

Porcine circovirus 2 (PCV-2) genotype update and proposal of a new genotyping methodology

G Franzo, J Segalés - PloS one, 2018 - journals.plos.org
Porcine circovirus 2 (PCV-2) is one of the most widespread viral infections of swine, causing
a remarkable economic impact because of direct losses and indirect costs for its control. As …

Porcine circovirus 2 genotypes, immunity and vaccines: Multiple genotypes but one single serotype

G Franzo, J Segalés - Pathogens, 2020 - mdpi.com
Identified for the first time in the 1990s, Porcine circovirus 2 (PCV-2) should not be
considered an emerging virus anymore. Nevertheless, many aspects of its biology and …

Full‐genome sequencing of porcine circovirus 3 field strains from Denmark, Italy and Spain demonstrates a high within‐Europe genetic heterogeneity

G Franzo, M Legnardi, CK Hjulsager… - Transboundary and …, 2018 - Wiley Online Library
Summary Porcine circovirus 3 (PCV 3) is a new species of the Circovirus genus, which has
recently been associated with different clinical syndromes. Its presence has been reported in …

Origin, genetic diversity, and evolutionary dynamics of novel porcine circovirus 3

G Li, W He, H Zhu, Y Bi, R Wang, G Xing… - Advanced …, 2018 - Wiley Online Library
Abstract Porcine circovirus 3 (PCV3) is a novel virus associated with acute PDNS (porcine
dermatitis and nephropathy syndrome)‐like clinical signs identified by metagenomic …

Insights into the epidemic characteristics and evolutionary history of the novel porcine circovirus type 3 in southern China

X Fu, B Fang, J Ma, Y Liu, D Bu, P Zhou… - Transboundary and …, 2018 - Wiley Online Library
Summary Porcine circovirus type 3 (PCV 3) is a newly identified circovirus from swine in the
USA, China and Poland. This novel circovirus has been associated with porcine dermatitis …

Porcine circovirus type 2 vaccines: commercial application and research advances

J Guo, L Hou, J Zhou, D Wang, Y Cui, X Feng, J Liu - Viruses, 2022 - mdpi.com
Porcine circovirus type 2 (PCV2) infection can lead to porcine circovirus-associated disease
(PCVAD), causing great economic losses to the global swine industry. Conventional …

Ten years of PCV2 vaccines and vaccination: Is eradication a possibility?

Z Afghah, B Webb, XJ Meng, S Ramamoorthy - Veterinary microbiology, 2017 - Elsevier
More than two decades after its emergence, porcine circovirus type 2 (PCV2) remains an
economically important swine pathogen. Commercial vaccines which were first introduced to …

PCV2d-2 is the predominant type of PCV2 DNA in pig samples collected in the US during 2014–2016

CT Xiao, KM Harmon, PG Halbur, T Opriessnig - Veterinary microbiology, 2016 - Elsevier
Abstract Porcine circovirus type 2 (PCV2) vaccination was introduced in the US in 2006 and
since has been adopted by most pig producers. While porcine circovirus associated disease …