[HTML][HTML] Roles of Hypoxia-Inducible Factor-Prolyl Hydroxylases in Aging and Disease
The prolyl hydroxylase domain-containing (PHD or EGL9-homologs) enzyme family is
mainly known for its role in the cellular response to hypoxia. HIF-PH inhibitors can stabilize …
mainly known for its role in the cellular response to hypoxia. HIF-PH inhibitors can stabilize …
Anti-fibrotic effects of statin drugs: A review of evidence and mechanisms
Fibrosis is a pathological repair process common among organs, that responds to tissue
damage by replacement with non-functional connective tissue. Despite the widespread …
damage by replacement with non-functional connective tissue. Despite the widespread …
Comparing generic drug markets in Europe and the United States: prices, volumes, and spending
Policy Points: Our study indicates that there are opportunities for cost savings in generic
drug markets in Europe and the United States. Regulators should make it easier for generic …
drug markets in Europe and the United States. Regulators should make it easier for generic …
[HTML][HTML] Statins utilization trends and expenditures in the US before and after the implementation of the 2013 ACC/AHA guidelines
A Matyori, CP Brown, A Ali, F Sherbeny - Saudi Pharmaceutical Journal, 2023 - Elsevier
Importance Statins are drugs of choice in treating hyperlipidemia and preventing or reducing
cardiovascular diseases. Purpose Explore statins utilization and expenditure trends in the …
cardiovascular diseases. Purpose Explore statins utilization and expenditure trends in the …
[HTML][HTML] Defining and measuring health poverty
P Clarke, G Erreygers - Social science & medicine, 2020 - Elsevier
Unlike other aspects of welfare (eg income), health has been relatively neglected when it
comes to defining and measuring aspects of poverty. The aim of the paper is twofold: first we …
comes to defining and measuring aspects of poverty. The aim of the paper is twofold: first we …
Trends in use of high-intensity statin therapy after myocardial infarction, 2011 to 2014
RS Rosenson, ME Farkouh, M Mefford, V Bittner… - Journal of the American …, 2017 - jacc.org
Background: Data prior to 2011 suggest that a low percentage of patients hospitalized for
acute coronary syndromes filled high-intensity statin prescriptions upon discharge. Black …
acute coronary syndromes filled high-intensity statin prescriptions upon discharge. Black …
Generic drugs in the United States: policies to address pricing and competition
The cost of prescription drugs in the United States continues to be a source of concern for
patients, caregivers, and policymakers. Drug prices typically decline rapidly once generic …
patients, caregivers, and policymakers. Drug prices typically decline rapidly once generic …
Determinants of market exclusivity for prescription drugs in the United States
The high prices of brand-name prescription drugs are a growing source of controversy in the
United States. Manufacturers of brand-name drugs can command high prices because they …
United States. Manufacturers of brand-name drugs can command high prices because they …
Trends in use and expenditures for brand-name statins after introduction of generic statins in the US, 2002-2018
Importance The high and increasing expenditures for prescription medications in the US is a
national problem. Objective To explore the association of generic statin competition on …
national problem. Objective To explore the association of generic statin competition on …
Twenty-year nationwide trends in statin utilization and expenditure in Denmark
In Denmark, statin therapy has increased tremendously over the past 20 years with great
variability in the proportionate use of different types of statins. Somewhat surprisingly, total …
variability in the proportionate use of different types of statins. Somewhat surprisingly, total …