Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

Salivary gland (SG) dysfunction, due to radiotherapy, disease, or aging, is a clinical
manifestation that has the potential to cause severe oral and/or systemic diseases and …

Intracellular Ca2+ signalling is a major signal transductional pathway in non-excitable cells,
responsible for the regulation of a variety of physiological functions. In the secretory …

Cancer is a major cause of death. The diversity of cancer types and the propensity of
cancers to acquire resistance to therapies, including new molecularly targeted and immune …

Salivary gland hypofunction is an adverse side effect associated with radiotherapy for head
and neck cancer patients. This study delineated metabolic changes at acute, intermediate …

Salivary glands are indirectly damaged during radiotherapy for head and neck cancer,
resulting in acute and chronic hyposalivation. Current treatments for radiation-induced …

Salivary glands secrete saliva, a mixture of proteins and fluids, which plays an extremely
important role in the maintenance of oral health. Loss of salivary secretion causes a dry …

Background: Altered intracellular Ca2+ homeostasis in neonatal platelets has been
previously reported. This study aims to examine the changes in the Ca2+ entry through the …

Transient receptor potential (TRP) channels are polymodal channels capable of sensing
environmental stimuli, which are widely expressed on the plasma membrane of cells and …