In eukaryotes, transcription of the diverse array of tens of thousands of protein-coding genes
is carried out by RNA polymerase II. The control of this process is predominantly mediated …

'Homeotic'transformations are developmental anomalies in which one part of the body
develops iiJ the likeness of another. Many cases of homeosis were described and the …

The murine oct-3 gene encodes a transcription factor containing a POU-specific domain and
a homeodomain. In marked contrast to other homeodomain-encoding genes, oct-3 is …

The maize P gene, which specifies red pigmentation of the kernel pericarp, cob, and other
floral organs, has been an important model since the early days of modern genetics. Here …

The activation of nuclear factor kappa B (NF-kappa B) has been implicated in the regulation
of transcription of a variety of genes and has been shown to be essential for the expression …

Exposure of skeletal myoblasts to growth factor-deficient medium results in transcriptional
activation of muscle-specific genes, including the muscle creatine kinase gene (mck). Tissue …

MyoD is a skeletal muscle-specific protein that is able to induce myogenesis in a wide
variety of cell types. In this report, we show that MyoD is a DNA binding protein capable of …

We describe the cDNA encoding the SV40 transcriptional enhancer factor 1 (TEF-1) and
show that its translation initiates exclusively at an AUU codon in vivo. Cloned TEF-1, which …

We used a yeast genetic screen to isolate cDNAs that encode a protein, SRF accessory
protein-l (SAP-l), that is recruited to the c-fos serum response element (ME) as part of a …

Serum response factor (SRF) is a transcription factor that binds the sequence CC (A/T) 6GG
found in a number of growth factor-inducible and muscle-specific promoters. We describe …