[HTML][HTML] Cryoimmunology: Opportunities and challenges in biomedical science and practice

NN Korpan, AN Goltsev, OI Dronov, MO Bondarovych - Cryobiology, 2021 - Elsevier
Autologous and allogeneic cryoimmunological medicine is a brand new branch of
biomedical science and clinical practice that examines the features and formation of the …

Dual-targeted therapeutic strategy combining CSC–DC-based vaccine and cisplatin overcomes chemo-resistance in experimental mice model

NE El-Ashmawy, ML Salem, EG Khedr… - Clinical and …, 2020 - Springer
Background and purpose Emerging evidence suggests that one of the main reasons of
chemotherapy treatment failure is the development of multi-drug resistance (MDR) …

Toxicity of nanocomplexes containing gadolinium orthovanadate nanoparticles and cholesterol

A Goltsev, N Babenko, Y Gaevska… - … Trace Element Research, 2022 - Springer
Previous studies have shown the ability of nanocomplexes (NCs), which consist of
nanoparticles (NPs) of orthovanadates of rare earth metals (GdYVO 4: Eu 3+) and …

A new strategy for enhancing antitumor immune response using dendritic cells loaded with chemo-resistant cancer stem-like cells in experimental mice model

NE El-Ashmawy, EA El-Zamarany, ML Salem… - Molecular …, 2019 - Elsevier
Background and aim Cancer stem cells (CSCs) are rare cell population present in the tumor
bulk that are thought to be the reason for treatment failure following chemotherapy in terms …

Proliferative activity of Ehrlich carcinoma cells after use of nanocomplexes

A Goltsev, NM Babenko, YO Gaevska… - … , and Their Applications …, 2023 - Springer
Investigation of functional state of tumor cells, peculiarities of the pathology development,
and sensitivity of tumor cells to the therapeutic agents is an urgent task of modern oncology …

Effect of different cryopreservation regimens on Ehrlich carcinoma growth

AM Goltsev, MO Bondarovych, NM Babenko… - Cell and Tissue …, 2019 - Springer
The freezing rate is a decisive factor in determining the purpose of using low temperatures,
ie, for cryoablation or cryobanking of tumor cells. The research aim was to determine effect …

Mechanisms of antitumor effect of nanomaterials based on rare earth orthovanadates

A Goltsev, Y Malyukin, N Babenko, Y Gaevska… - … , and Their Applications …, 2020 - Springer
In experimental conditions in vivo the possibility of using GdYEuVO4 nanoparticles and
hybrid nanocomplexes synthesized on their basis for the identification of cancer cells and …

Antitumor activity of spherical nanoparticles GdYVO4:Eu3+ depends on pre-incubation time

AM Goltsev, YV Malyukin, NM Babenko… - Applied …, 2020 - Springer
The significance of tumor cells incubation with spherical nanoparticles based on
orthovanadates of rare-earth elements activated by europium GdYVO 4: Eu 3+ in the …

Tumor heterogeneity: An important determinant for efficacy and safety in nanoparticle anticancer gene therapy

PK Suresh - Trends in Biotechnology, 2018 - cell.com
Models of tumor heterogeneity should mimic perfusion in the tumor mass and consider
cancer stem cell hierarchy and convertibility. Other important factors include epigenomic …

Роль активних форм кисню в реалізації протипухлинної дії нанокомплексів на основі наночастинок GdYEuVO4 і холестерину

A Goltsev, M Bondarovych, Y Gaevska… - Innovative Biosystems …, 2024 - ibb.kpi.ua
Проблематика. Експериментальне вивчення протипухлинної дії нанокомплексів (НК),
що складаються з наночастинок GdYEuVO4 і холестерину, свідчить про доцільність їх …