[HTML][HTML] Cytokine Storm in COVID-19: Exploring IL-6 Signaling and Cytokine-Microbiome Interactions as Emerging Therapeutic Approaches

TG Paranga, I Mitu, M Pavel-Tanasa, MF Rosu… - International Journal of …, 2024 - mdpi.com
IL-6 remains a key molecule of the cytokine storms characterizing COVID-19, exerting both
proinflammatory and anti-inflammatory effects. Emerging research underscores the …

COVID-19 and Laboratory Markers from Romanian Patients—A Narrative Review

O Musat, VB Sorop, MI Sorop, V Lazar, DT Marti… - Life, 2023 - mdpi.com
COVID-19 has significantly impacted the whole world, and Romania was no exception.
Biomarkers play a crucial role in understanding and managing the disease. However …

Distinct soluble immune checkpoint profiles characterize COVID-19 severity, mortality and SARS-CoV-2 variant infections

TG Paranga, M Pavel-Tanasa… - Frontiers in …, 2024 - frontiersin.org
Introduction Over the past four years, the COVID-19 pandemic has posed serious global
health challenges. The severe form of disease and death resulted from the failure of immune …

Predictive biomarkers of mortality in patients with severe COVID-19 hospitalized in intensive care unit

SMFR dos Santos Medeiros, BMN Sousa Lino… - Frontiers in …, 2024 - frontiersin.org
Objectives This study was performed to identify predictive markers of worse outcomes in
patients with severe COVID-19 in an intensive care unit. Methods Sixty patients with severe …

The role of neutrophil in COVID-19: positive or negative

N Rong, X Wei, J Liu - Journal of Innate Immunity, 2024 - karger.com
The Role of Neutrophil in COVID-19 — Positive or Negative Page 1 J Innate Immun , DOI:
10.1159/000535541 Received: September 16, 2023 Accepted: November 27, 2023 Published …

Effects of COVID-19 on the liver and mortality in patients with SARS-CoV-2 pneumonia caused by delta and non-Delta variants: an analysis in a single centre

M Muntean, V Briciu, M Lupse, D Colcear… - Pharmaceuticals, 2023 - mdpi.com
The aim of this study was to ascertain patient characteristics, outcomes, and liver injuries in
patients infected with different SARS-CoV-2 variants. Data from consecutive adult patients …

Demystifying COVID-19 mortality causes with interpretable data mining

X Qian, Z Zuo, D Xu, S He, C Zhou, Z Wang, S Xie… - Scientific Reports, 2024 - nature.com
While COVID-19 becomes periodical, old individuals remain vulnerable to severe disease
with high mortality. Although there have been some studies on revealing different risk factors …

Association of COVID-19 with acute and post-acute risk of multiple different complications and mortality in patients infected with omicron variant stratified by initial …

EYF Wan, R Zhang, S Mathur, VKC Yan, FTT Lai… - BMC medicine, 2024 - Springer
Background Few studies have attempted to use clinical and laboratory parameters to stratify
COVID-19 patients with severe versus non-severe initial disease and evaluate age-specific …

[HTML][HTML] Green tea extract reduced lipopolysaccharide-induced inflammation in L2 cells as acute respiratory distress syndrome model through genes and cytokine pro …

D Priyandoko, W Widowati, L Lenny… - Avicenna Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Acute Respiratory Distress Syndrome (ARDS) is a severe lung inflammatory
condition that has the capacity to impair gas exchange and lead to hypoxemia. This …

Normalization of eosinophil count is predictive of oxygen weaning over the course of COVID-19 infection among hospitalized adults during the first wave of 2020 …

B Davido, K Jaffal, A Saleh-Mghir, I Vaugier… - Frontiers in …, 2024 - frontiersin.org
Background Understanding COVID-19 outcomes remains a challenge. While numerous
biomarkers have been proposed for severity at admission, limited exploration exists for …