Polysaccharide was a class of macromolecular substance with various bioactive functions.
Gut symbiotic microorganisms could utilize the polysaccharides from various sources, thus …

Sigma factors are multi-domain subunits of bacterial RNA polymerase (RNAP) that play
critical roles in transcription initiation, including the recognition and opening of promoters as …

Transcription initiation is the crucial focal point of gene expression in prokaryotes. The key
players in this process, sigma factors (σs), associate with the catalytic core RNA polymerase …

Respiratory infections with Pseudomonas aeruginosa and Burkholderia cepacia play a
major role in the pathogenesis of cystic fibrosis (CF). This review summarizes the latest …

Various gram-negative animal and plant pathogens use a novel, sec-independent protein
secretion system as a basic virulence mechanism. It is becoming increasingly clear that …

▪ Abstract Promoter recognition in eubacteria is carried out by the initiation factor sigma,
which binds RNA polymerase and initiates transcription. Cells have one housekeeping …

Transcription of DNA is a fundamental process in all cellular organisms. The enzyme
responsible for transcription, RNA polymerase, is conserved in general architecture and …

Bacterial sigma (σ) factors are an essential component of RNA polymerase and determine
promoter selectivity. The substitution of one σ factor for another can redirect some or all of …

Members of the σ 70 family of sigma factors are components of the RNA polymerase
holoenzyme that direct bacterial or plastid core RNA polymerase to specific promoter …

The leading cause of mortality in patients with cystic fibrosis (CF) is respiratoy failure due in
large part to chronic lung infection with Pseudomonas aeruginosa strains that undergo …