Exosomes derived from human umbilical cord mesenchymal stem cells accelerate cutaneous wound healing by enhancing angiogenesis through delivering …

J Liu, Z Yan, F Yang, Y Huang, Y Yu, L Zhou… - Stem cell reviews and …, 2021 - Springer
The underlying mechanisms of human umbilical cord mesenchymal stem cells (hucMSCs)
and their exosomes (hucMSC-Exs), which play significant roles in skin wound healing …

[HTML][HTML] Analysis of common and characteristic actions of Panax ginseng and Panax notoginseng in wound healing based on network pharmacology and meta …

Z Wang, X Xie, M Wang, M Ding, S Gu, X Xing… - Journal of Ginseng …, 2023 - Elsevier
In recent years, an increasing number of reports have explored the wound healing
mechanism of these two traditional Chinese herbal medicines-Panax ginseng and Panax …

Patient-driven discovery of CCN1 to rescue cutaneous wound healing in diabetes via the intracellular EIF3A/CCN1/ATG7 signaling by nanoparticle-enabled delivery

JS Jiang, J Zang, Y Ru, Y Luo, JK Song, Y Luo, XY Fei… - Biomaterials, 2022 - Elsevier
Diabetic ulcers (DUs), a devastating complication of diabetes, are intractable for limited
effective interventions in clinic. Based on the clinical samples and bioinformatic analysis, we …

Ablation of endothelial Atg7 inhibits ischemia-induced angiogenesis by upregulating Stat1 that suppresses Hif1a expression

H Yao, J Li, Z Liu, C Ouyang, Y Qiu, X Zheng, J Mu… - Autophagy, 2023 - Taylor & Francis
Ischemia-induced angiogenesis is critical for blood flow restoration and tissue regeneration,
but the underlying molecular mechanism is not fully understood. ATG7 (autophagy related 7) …

Negative pressure wound therapy promotes wound healing by suppressing macrophage inflammation in diabetic ulcers

H Song, Y Xu, W Chang, J Zhuang, X Wu - Regenerative Medicine, 2020 - Taylor & Francis
Aim: This work aims to explore the biological role of negative pressure wound therapy
(NPWT) in the treatment of diabetic ulcer. Materials & methods: Full-thickness skin defects …

Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases

J Liu, Y Xiao, L Cao, S Lu, S Zhang, R Yang… - Communications …, 2024 - nature.com
Autophagy is a dynamic self-renovation biological process that maintains cell homeostasis
and is responsible for the quality control of proteins, organelles, and energy metabolism …

Endothelial Autophagy-related gene 7 Contributes to High Fat Diet-Induced Obesity

G Ren, S Bhatnagar, ME Young, T Lee, J Kim - Molecular Metabolism, 2025 - Elsevier
Objective Obesity-associated metabolic dysfunction is a major public health concern
worldwide. Endothelial dysfunction is a hallmark of metabolic dysfunction, and endothelial …

A scATAC-seq atlas of stasis zone in rat skin burn injury wound process

R Li, J Li, S Liu, X Guo, J Lu, T Wang, J Chen… - Frontiers in Cell and …, 2025 - frontiersin.org
Burn injuries often leave behind a “stasis zone”, a region of tissue critically important for
determining both the severity of the injury and the potential for recovery. To understand the …

Single-cell RNA-seq and bulk-seq identify RAB17 as a potential regulator of angiogenesis by human dermal microvascular endothelial cells in diabetic foot ulcers

H Du, S Li, J Lu, L Tang, X Jiang, X He, J Liang… - Burns & …, 2023 - academic.oup.com
Background Angiogenesis is crucial in diabetic wound healing and is often impaired in
diabetic foot ulcers (DFUs). Human dermal microvascular endothelial cells (HDMECs) are …

ALM induces cellular quiescence in the surgical margin 3 days following liver resection, hemorrhage, and shock

HL Letson, JL Morris, E Biros, GP Dobson - journal of surgical research, 2022 - Elsevier
Introduction The liver has a remarkable capacity to regenerate but not the resected lobe. Our
aim was to examine the expression of a number of key genes of metabolism, proliferation …