Intracerebral haemorrhage (ICH) is the most lethal subtype of stroke but currently lacks
effective treatment. Microglia are among the first non-neuronal cells on the scene during the …

Intracerebral haemorrhage accounts for about 10–15% of all strokes and is associated with
high mortality and morbidity. No successful phase 3 clinical trials for this disorder have been …

Oxidative stress plays an important role in secondary brain injury (SBI) after intracerebral
hemorrhage (ICH), but the underling mechanism has not been fully elucidated. Recently, the …

Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …

Intracerebral hemorrhage (ICH) is a subtype of stroke with high mortality and morbidity.
When a diseased artery within the brain bursts, expansion and absorption of the resulting …

Microglia are the first responders to intracerebral hemorrhage, but their precise role in
intracerebral hemorrhage remains to be defined. Microglia are the only type of brain cells …

Background and Purpose—Neuroinflammatory processes contribute to secondary neuronal
damage after intracerebral hemorrhage. We aimed to characterize the time course of brain …

Intracerebral hemorrhage (ICH) is a common and often fatal stroke subtype for which
specific therapies and treatments remain elusive. To address this, many recent experimental …

Intracerebral hemorrhage (ICH) is a major health concern, with high rates of mortality and
morbidity and no highly effective clinical interventions. Basic research in animal models of …

Animal models of stroke contribute to the development of better stroke prevention and
treatment through studies investigating the pathophysiology of different stroke subtypes and …