Modifications of lean mass are a frequent critical determinant in the pathophysiology and
progression of heart failure (HF). Sarcopenia may be considered one of the most important …

Body wasting is a serious complication that affects a large proportion of patients with heart
failure. Muscle wasting, also known as sarcopenia, is the loss of muscle mass and strength …

Skeletal muscle satellite cells are considered to play a crucial role in muscle fiber
maintenance, repair and remodeling. Our knowledge of the role of satellite cells in muscle …

In clinical trials, biochemical markers provide useful information on the drug's mode of
action, therapeutic response and side effect monitoring and can act as surrogate endpoints …

Sarcopenia is a geriatric syndrome with a significant impact on older patients' quality of life,
morbidity and mortality. Despite the new available criteria, its early diagnosis remains …

Muscle wasting is associated with a wide range of catabolic diseases. This debilitating loss
of muscle mass and functional capacity reduces the quality of life and increases the risks of …

Loss of muscle mass, or sarcopenia, is nearly universal in cirrhosis and adversely affects
patient outcome. The underlying cross-talk between the liver and skeletal muscle mediating …

Sarcopenia, the lowered skeletal muscle mass, weakened skeletal muscle strength, and
reduced physical performance with aging, is a component of frailty and high-risk factor for …

Sarcopenia is an age-related geriatric syndrome that is characterized by a progressive loss
of muscle mass, strength and function. Chronic heart failure (CHF), the final stage of various …

Cachexia is the loss of lean body mass (LBM) that affects a large proportion of dogs and cats
with congestive heart failure (CHF), chronic kidney disease (CKD), cancer, and a variety of …