Anemia at older age: etiologies, clinical implications, and management

R Stauder, P Valent, I Theurl - Blood, The Journal of the …, 2018 - ashpublications.org
Anemia is quite frequently diagnosed in older individuals and is a key indicator of various
reactive and clonal conditions. Many underlying diseases, like myelodysplastic syndrome …

Oxidative stress, eryptosis and anemia: a pivotal mechanistic nexus in systemic diseases

R Bissinger, AAM Bhuyan, SM Qadri… - The FEBS …, 2019 - Wiley Online Library
The average lifespan of circulating erythrocytes usually exceeds hundred days. Prior to that,
however, erythrocytes may be exposed to oxidative stress in the circulation which could …

[HTML][HTML] Effects of IL-1β, IL-6 and IL-8 on erythrocytes, platelets and clot viscoelasticity

J Bester, E Pretorius - Scientific reports, 2016 - nature.com
Complex interactions exist between cytokines and the interleukin family plays a fundamental
role in inflammation. Particularly circulating IL-1β, IL-6 and IL-8 are unregulated in systemic …

[HTML][HTML] Molecular mechanisms and pathophysiological significance of eryptosis

SA Alghareeb, MA Alfhili, S Fatima - International Journal of Molecular …, 2023 - mdpi.com
Despite lacking the central apoptotic machinery, senescent or damaged RBCs can undergo
an unusual apoptosis-like cell death, termed eryptosis. This premature death can be caused …

[PDF][PDF] A comprehensive review on eryptosis

E Pretorius, JN du Plooy, J Bester - Cellular Physiology and …, 2016 - karger.com
Erythrocytes (RBCs) are extremely sensitive cells, and although they do not have nuclei and
mitochondria, are important health indicators. This is particularly true because, during …

Anemia in the frail, elderly patient

G Röhrig - Clinical interventions in aging, 2016 - Taylor & Francis
Anemia and frailty are two common findings in geriatric patients and have been shown to be
associated with poor outcomes in this patient group. Recent studies have contributed to the …

Erythrocytes as model cells for biocompatibility assessment, cytotoxicity screening of xenobiotics and drug delivery

M Podsiedlik, M Markowicz-Piasecka… - Chemico-Biological …, 2020 - Elsevier
Erythrocytes (RBCs) represent the main cell component in circulation and recently have
become a topic of intensive scientific interest. The relevance of erythrocytes as a model for …

Casein kinase 1α mediates eryptosis: a review

A Tkachenko, A Onishchenko - Apoptosis, 2023 - Springer
Eryptosis is a coordinated non-lytic cell death of erythrocytes characterized by cell
shrinkage, cell membrane scrambling, Ca2+ influx, ceramide accumulation, oxidative stress …

[HTML][HTML] Mercury chloride affects band 3 protein-mediated anionic transport in red blood cells: role of oxidative stress and protective effect of olive oil polyphenols

P Perrone, S Spinelli, G Mantegna, R Notariale… - Cells, 2023 - mdpi.com
Mercury is a toxic heavy metal widely dispersed in the natural environment. Mercury
exposure induces an increase in oxidative stress in red blood cells (RBCs) through the …

[HTML][HTML] Autoimmune hemolytic anemia: current knowledge and perspectives

SS Michalak, A Olewicz-Gawlik, J Rupa-Matysek… - Immunity & …, 2020 - Springer
Autoimmune hemolytic anemia (AIHA) is an acquired, heterogeneous group of diseases
which includes warm AIHA, cold agglutinin disease (CAD), mixed AIHA, paroxysmal cold …