Over the last decade, developments in molecular profiling have radically altered the
diagnosis, classification, and management of numerous cancer types, with primary brain …

The updated 2016 edition of the World Health Organization (WHO) Classification of Tumours
of the Central Nervous System (CNS) uses molecular parameters and the histology to define …

The “integrated diagnosis” for infiltrating gliomas in the 2016 revised World Health
Organization (WHO) classification of tumors of the central nervous system requires …

This review is based on a presentation given at the Hans Popper Hepatopathology Society
companion meeting at the 2019 United States and Canadian Academy of Pathology Annual …

Immunohistochemistry represents an indispensable complement to an epidemiology and
morphology-driven approach to tumor diagnosis and site of origin assignment. This review …

A growing body of epidemiologic and tumor genomic research has identified an important
role for telomere maintenance in glioma susceptibility, initiation, and prognosis. Telomere …

Glioblastoma (GBM) is the most common malignant adult primary brain tumor. Despite its
high lethality, a small proportion of patients have a relatively long overall survival (OS). Here …

Identification of recurrent tumour‐specific chromosomal translocations and novel fusion
oncogenes has important diagnostic, therapeutic and prognostic implications. Over the past …

Background Glioma is one of the most common malignant brain tumors and exhibits low
resection rate and high recurrence risk. Although a large number of glioma studies powered …

Objective The objective of the study was to summarize the clinical characteristics, histo-
genomic profiles, management strategies, and survival outcomes of H3K27M-altered adult …