Evaluation of the binding properties of drugs to albumin from DSC thermograms
I Sedov, A Nikiforova, D Khaibrakhmanova - International journal of …, 2020 - Elsevier
There is a demand in rapid and robust methods to determine the affinity of drugs to
receptors, enzymes, and transport proteins. Differential scanning calorimetry (DSC) is a …
receptors, enzymes, and transport proteins. Differential scanning calorimetry (DSC) is a …
Intercalative interaction of the anticancer drug mitoxantrone with double stranded DNA: A calorimetric characterization of the energetics
The interaction of the anticancer agent mitoxantrone with DNA was investigated using
microcalorimetry. The results show that the binding of mitoxantrone to DNA was …
microcalorimetry. The results show that the binding of mitoxantrone to DNA was …
Novel 18-crown-6-ether containing mono-and bisstyryl dyes derived from pyridine moiety as fluorescent dyes for non-covalent interaction with DNA
AY Lebedeva, OA Fedorova, VB Tsvetkov… - Dyes and …, 2018 - Elsevier
Bisstyrylpyridine dyes 1 and 2, in which two styrylpyridine moieties are connected to each
other through the oxo-or azacrown ether unit, and their monomer analogues 3 and 4 have …
other through the oxo-or azacrown ether unit, and their monomer analogues 3 and 4 have …
[图书][B] Titration Calorimetry: From Concept to Application
LD Hansen, MK Transtrum, CF Quinn - 2018 - Springer
This brief provides an introduction to calorimetry in general and to titration calorimetry
specifically. The intended audience is college students and others who are unfamiliar with …
specifically. The intended audience is college students and others who are unfamiliar with …
Structure, thermodynamics and energetics of drug-DNA interactions: computer modeling and experiment
MP Evstigneev, AV Shestopalova - Application of computational …, 2014 - Springer
In this chapter we demonstrate the large usefulness of using complex approach for
understanding the mechanism of binding of biologically active compounds (antitumour …
understanding the mechanism of binding of biologically active compounds (antitumour …
[HTML][HTML] Thermal analysis of ligand-DNA interaction: determination of binding parameters
E Bereznyak, N Gladkovskaya, E Dukhopelnykov… - Aims …, 2015 - aimspress.com
The review discusses the methods of thermodynamic analysis of reactions of non-covalent
binding of biologically active compounds with DNA, which is a key constituent of cell …
binding of biologically active compounds with DNA, which is a key constituent of cell …
Modeling of heat absorption curves for ligand-competitor-DNA triple system
EV Dukhopelnikov - Biophysical Bulletin, 2014 - periodicals.karazin.ua
The model for a ligand-competitor-DNA triple system is suggested. The model is based on
chemical equilibria equations and allows one to analyze DSC experimental data. It is shown …
chemical equilibria equations and allows one to analyze DSC experimental data. It is shown …
Related Topics in Calorimetry
LD Hansen, MK Transtrum, CF Quinn… - … : From Concept to …, 2018 - Springer
Many analytical applications of titration calorimetry were developed beginning in the 1960s
when thermistors became available. Thermistors, with time constants< 1 s and sufficient …
when thermistors became available. Thermistors, with time constants< 1 s and sufficient …
Thermodynamic analysis of ligand-DNA complex formation from the spectrophotometric data
H Anastasiia - 2015 International Young Scientists Forum on …, 2015 - ieeexplore.ieee.org
DNA is the target for many anticancer and antitumor drugs. Therefore determination of the
thermodynamic parameters of ligands-DNA interaction for prediction of biological activity at …
thermodynamic parameters of ligands-DNA interaction for prediction of biological activity at …