'Objective': To review how different classes of immunosuppressants affect wound
healing.'Data Sources': A literature search was conducted in PubMed, Google Scholar, and …

Conclusions Corticosteroids and mechanistic target of rapamycin inhibitors most
consistently demonstrate detrimental effects on wound healing. For other classes of …

Total proctocolectomy (TPC) cures a patient of the intestinal manifestation of chronic
ulcerative colitis. The timing of surgery during the illness will influence the choice of …

Objective Treatment of Crohn's disease (CD) with anti-tumor necrosis factor α (TNFα)
decreases intestinal inflammation, but the effect on fibrosis remains unclear. We …

Background: In this experimental study, simplicity of measurement and wound tensile
strength of wounds fixed by simple interrupted percutaneous suture (SIPS) and intradermal …

Βackground and aim: Infliximab is effective in the induction and maintenance of remission in
Crohn's disease. Whether, the perioperative administration of anti-TNF-a compromises …

Objective: A review of recent literature to provide clinicians with an understanding of how
different classes of immunosuppressants affect wound healing. Data sources: A literature …

Background Anastomotic dehiscence is the most severe complication of colorectal surgery
and its incidence increases in the presence of infection. It has been reported that immune …

The real impact of biological therapy (anti-TNF agents) in abdominal operations secondary
to Crohn's disease is a matter of debate in the international literature. Several studies …

PURPOSE: To evaluate the influence of carbon dioxide pneumoperitoneum on abdominal
wall wound healing in rats. METHODS: Eighty rats underwent laparotomy, segmental left …