BRAF represents one of the most frequently mutated protein kinase genes in human
tumours. The mutation is commonly tested in pathology practice. BRAF mutation is seen in …

The NCCN Guidelines for Thyroid Carcinoma provide recommendations for the
management of different types of thyroid carcinoma, including papillary, follicular, Hürthle …

Thyroid cancer is the most common malignancy of the endocrine system, encompassing
different entities with distinct histological features and clinical behavior. The diagnostic …

BTA_Guidelines_for_the_Management_of_Thyroid Cancer_E Page 1 CLINICAL
ENDOCRINOLOGY VOLUME 81 SUPPLEMENT 1 JULY 2014 THE CLINICAL JOURNAL OF …

Objectives: To correlate thyroid cancer genotype with histology and outcomes. Background:
The prognostic significance of molecular signature in thyroid cancer (TC) is undefined but …

Background: Gene panels are routinely used to assess predisposition to hereditary cancers
by simultaneously testing multiple susceptibility genes and/or variants. More recently …

Indeterminate thyroid cytology (Bethesda III and IV) corresponds to follicular-patterned
benign and malignant lesions, which are particularly difficult to differentiate on cytology …

Background Thyroid nodules are usually diagnosed using fine-needle aspiration (FNA). The
sensitivity limitations of FNA result in 10–30% of nodules being classified as “indeterminate” …

Background The diagnosis of indeterminate lesions of the thyroid is a challenge in
cytopathology practice. Indeed, up to 30% of cases lack the morphological features needed …

Purpose: To evaluate the diagnostic role of core needle biopsy (CNB) in sonographically
suspicious thyroid nodules with initially benign cytologic results through a histologic analysis …