Diffuse midline gliomas (DMGs) are devastating pediatric brain tumors recognized as the
leading cause of cancer-related death in children. DMGs are high-grade gliomas (HGGs) …

Introduction ClpP is a highly conserved serine protease that plays a crucial role in
maintaining protein homeostasis in both bacterial cells and human mitochondria. Several …

Introduction Sorafenib, an FDA-approved standard chemotherapy for advanced
hepatocellular carcinoma, is associated with numerous adverse effects that significantly …

Caseinolytic protease P (ClpP) responsible for the proteolysis of damaged or misfolded
proteins plays a critical role in proteome homeostasis. MtbClpP1P2, a ClpP enzyme …

The caseinolytic protease (ClpP)-producing strain CHFM, isolated from Algerian goat milk,
was identified as Lactiplantibacillus pentosus through 16 S rRNA sequence analysis. The …

Breast cancer cells exhibit metabolic heterogeneity based on tumour aggressiveness.
Glycolysis and mitochondrial respiration are two major metabolic pathways for ATP …

Transcription of the mitochondrial genome is essential for the maintenance of oxidative
phosphorylation (OXPHOS) and other functions directly related to this unique genome …

Tumor-homing neural stem cell (NSC) therapy is emerging as a promising treatment for
aggressive cancers of the brain. Despite their success, developing tumor-homing NSC …

In cells, proteins are synthesized, function, and degraded (dead). Protein synthesis (spring)
is important for the life of proteins. However, how proteins die is equally important for …

Breast cancer is the most commonly diagnosed cancer worldwide. Metal metabolism is
pivotal for regulating cell fate and drug sensitivity in breast cancer. Iron and copper are …