Antibiotics in periodontal therapy: advantages and disadvantages

J Slots, TE Rams - Journal of clinical periodontology, 1990 - Wiley Online Library
Antibiotic treatment of periodontitis aims at eradicating or controlling specific pathogens.
Prime candidates for antibiotic therapy are patients with recently diagnosed active …

Tetracyclines inhibit connective tissue breakdown: new therapeutic implications for an old family of drugs

LM Golub, NS Ramamurthy… - Critical Reviews in …, 1991 - journals.sagepub.com
Tetracyclines have long been considered useful adjuncts in peridontal therapy based on
their antimicrobial efficacy against putative periodontopathogens. However, recently these …

[图书][B] The periodontium

HE Schroeder - 2012 - books.google.com
In their contribution to the first edition of this Handbook, entitled" The Teeth," LEHNER and
PLENK (1936) discussed the tissues constituting the" perio dontium" rather briefly. In …

Suppression of the periodontopathic microflora in localized juvenile periodontitis by systemic tetracycline

J Slots, BG Rosling - Journal of clinical periodontology, 1983 - Wiley Online Library
Since recent studies have implicated Actinobacillus actinomycetemcomitans in the etiology
of localized juvenile periodontitis, this investigation determined the effectiveness of …

Low‐dose doxycycline therapy: Effect on gingival and crevicular fluid collagenase activity in humans

LM Golub, S Ciancio, NS Ramamurthy… - Journal of …, 1990 - Wiley Online Library
Tetracyclines are now recognized to have non‐antimicrobial properties with therapeutic
potential‐for example, these agents can inhibit pathologic collagenolysis by blocking …

Antibiotic resistance in an in vitro subgingival biofilm model

MJ Sedlacek, C Walker - Oral microbiology and immunology, 2007 - Wiley Online Library
Introduction: The purpose of this study was to utilize an in vitro biofilm model of subgingival
plaque to investigate resistances in subgingival biofilm communities to antibiotics commonly …

Modulation of matrix metalloproteinase activities in periodontitis as a treatment strategy.

ME Ryan, LM Golub - Periodontology 2000, 2000 - search.ebscohost.com
Focuses on the role of matrix metalloproteinase activities in physiological and pathological
events of periodontitis. Degradation of proteoglycan and fibronectin; Reduction of bacterial …

Tetracyclines in the management of periodontal diseases: A review

RA Seymour, PA Heasman - Journal of clinical periodontology, 1995 - Wiley Online Library
Periodontal diseases essentially comprise a group of oral infections whose primary
aetiological factor is dental plaque. Removal of the cause (and its effects) is the primary aim …

Prevalence and antimicrobial susceptibility of Enterobacteriaceae, Pseudomonadaceae and Acinetobacter in human periodontitis

J Slots, D Feik, TE Rams - Oral microbiology and immunology, 1990 - Wiley Online Library
This study examined the occurrence of non‐oral gram‐negative facultatively anaerobic rods
in advanced adult periodontitis. Speciation and in vitro antimicrobial susceptibility testing …

Clinical responses following periodontal treatment by local drug delivery

JM Goodson, PE Hogan… - Journal of periodontology, 1985 - Wiley Online Library
a 4‐quadrant, single‐blind study was designed to test the efficacy of periodontal disease
therapy by local drug delivery. A delivery system made of extruded ethylene vinyl acetate …