Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model

RB Price, R Duman - Molecular psychiatry, 2020 - nature.com
Chronic stress and depressive-like behaviors in basic neuroscience research have been
associated with impairments of neuroplasticity, such as neuronal atrophy and synaptic loss …

[HTML][HTML] Toward a wiring diagram understanding of appetite control

ML Andermann, BB Lowell - Neuron, 2017 - cell.com
Prior mouse genetic research has set the stage for a deep understanding of appetite
regulation. This goal is now being realized through the use of recent technological …

Thirst regulates motivated behavior through modulation of brainwide neural population dynamics

WE Allen, MZ Chen, N Pichamoorthy, RH Tien… - Science, 2019 - science.org
INTRODUCTION Motivational drives are internal states that can explain why animals
adaptively display distinct behaviors in response to the same external stimulus …

Why do people hurt themselves? A new conceptual model of nonsuicidal self-injury

JM Hooley, JC Franklin - Clinical psychological science, 2018 - journals.sagepub.com
The motivation to avoid pain and injury is a fundamental instinct, crucial to the survival of
individuals and species. Yet, each year, millions of people purposefully and directly injure …

[HTML][HTML] Acute social isolation evokes midbrain craving responses similar to hunger

L Tomova, KL Wang, T Thompson, GA Matthews… - Nature …, 2020 - nature.com
When people are forced to be isolated from each other, do they crave social interactions? To
address this question, we used functional magnetic resonance imaging to measure neural …

[HTML][HTML] Active inference, homeostatic regulation and adaptive behavioural control

G Pezzulo, F Rigoli, K Friston - Progress in neurobiology, 2015 - Elsevier
We review a theory of homeostatic regulation and adaptive behavioural control within the
Active Inference framework. Our aim is to connect two research streams that are usually …

Evolving concepts of emotion and motivation

KC Berridge - Frontiers in psychology, 2018 - frontiersin.org
This review takes a historical perspective on concepts in the psychology of motivation and
emotion, and surveys recent developments, debates and applications. Old debates over …

The physiological control of eating: signals, neurons, and networks

AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Addiction and stress: An allostatic view

GF Koob, J Schulkin - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Allostasis, or stability through change, has most often been linked with challenges to
homeostasis, in which repeated challenges or stressors produce sufficient allostatic load to …

The neuroscience of emotion: A new synthesis

R Adolphs, DJ Anderson - 2018 - torrossa.com
Emotions are one of the most apparent and important aspects of our lives, yet have
remained one of the most enigmatic to explain scienti cally. On the one hand, nothing seems …