Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Brain tumors, although rare, contribute to distinct mortality and morbidity at all ages.
Although there are few therapeutic options for brain tumors, enhanced biological …

Glioblastoma (GBM) is an intractable malignancy with high recurrence and mortality.
Combinatorial therapy based on temozolomide (TMZ) and cisplatin (CDDP) shows …

Glioma is one of the most common and lethal brain tumors. Surgical resection followed by
radiotherapy plus chemotherapy is the current standard of care for patients with glioma. The …

Glioblastoma (GBM) represents almost half of primary brain tumors, and its standard
treatment with the alkylating agent temozolomide (TMZ) is not curative. Treatment failure is …

Long-noncoding RNAs (lncRNAs) have been shown to participate in sensitizing or de-
sensitizing cancer cells to chemical drugs during cancer therapeutics. Notably, a plethora of …

A glioblastoma (GBM) is one of the most aggressive, infiltrative, and treatment-resistant
malignancies of the central nervous system (CNS). The current standard of care for GBMs …

Introduction Glioblastoma is a primary brain tumor with a poor prognosis despite multimodal
therapy including surgery, radiotherapy and alkylating chemotherapy. Novel therapeutic …

Glioblastoma (GBM) is the most prevalent and aggressive tumor in the central nervous
system. Surgical resection followed by concurrent radiotherapy (ionizing radiation [IR]) and …

Glioma is the most common primary intracranial malignancy in the central nervous system.
At present, the most important treatment option is surgical resection of the tumor combined …