Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …
Potential utility of liquid biopsy as a diagnostic and prognostic tool for the assessment of solid tumors: implications in the precision oncology
Liquid biopsy is a technique that utilizes circulating biomarkers in the body fluids of cancer
patients to provide information regarding the genetic landscape of the cancer. It is emerging …
patients to provide information regarding the genetic landscape of the cancer. It is emerging …
Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts
Cancer is as unique as the person fighting it. With the exception of a few biomarker-driven
therapies, patients go through rounds of trial-and-error approaches to find the best …
therapies, patients go through rounds of trial-and-error approaches to find the best …
A decision support framework for genomically informed investigational cancer therapy
F Meric-Bernstam, A Johnson, V Holla… - Journal of the …, 2015 - academic.oup.com
Rapidly improving understanding of molecular oncology, emerging novel therapeutics, and
increasingly available and affordable next-generation sequencing have created an …
increasingly available and affordable next-generation sequencing have created an …
Zebrafish avatars towards personalized medicine—a comparative review between avatar models
B Costa, MF Estrada, RV Mendes, R Fior - Cells, 2020 - mdpi.com
Cancer frequency and prevalence have been increasing in the past decades, with
devastating impacts on patients and their families. Despite the great advances in targeted …
devastating impacts on patients and their families. Despite the great advances in targeted …
A tale of exosomes and their implication in cancer
Cancer is a cause of high deaths worldwide and also a huge burden for the health system.
Cancer cells have unique properties such as a high rate of proliferation, self-renewal …
Cancer cells have unique properties such as a high rate of proliferation, self-renewal …
Improving the CellSearch® system
JF Swennenhuis, G van Dalum, LL Zeune… - Expert review of …, 2016 - Taylor & Francis
ABSTRACT Introduction: The CellSearch® CTC test enumerates tumor cells present in 7.5
ml blood of cancer patients. improvements, extensions and different utilities of the cellsearch …
ml blood of cancer patients. improvements, extensions and different utilities of the cellsearch …
Path toward precision oncology: review of targeted therapy studies and tools to aid in defining “actionability” of a molecular lesion and patient management support
Precision medicine trials and targeted therapies have shifted to the forefront of oncology.
Although targeted therapies have shown initial promise, implementation across the broad …
Although targeted therapies have shown initial promise, implementation across the broad …
Recent advances in the development of nanoparticles for multimodality imaging and therapy of cancer
M Liu, RC Anderson, X Lan, PS Conti… - Medicinal Research …, 2020 - Wiley Online Library
This review explores recent work directed toward the development of nanoparticles (NPs) for
multimodality cancer imaging and targeted cancer therapy. In the growing era of precision …
multimodality cancer imaging and targeted cancer therapy. In the growing era of precision …
Clinical actionability enhanced through deep targeted sequencing of solid tumors
BACKGROUND Further advances of targeted cancer therapy require comprehensive in-
depth profiling of somatic mutations that are present in subpopulations of tumor cells in a …
depth profiling of somatic mutations that are present in subpopulations of tumor cells in a …