Medicinal Spice, Aframomum melegueta: An Overview of the Phytochemical Constituents, Nutritional Characteristics, and Ethnomedicinal Values for Sustainability

MC Ogwu, A Dunkwu-Okafor, IA Omakor… - … : Applications and Trends, 2024 - Springer
This chapter explores the botanical characteristics, traditional uses, culinary applications,
and medicinal properties of the medicinal spice, Afromomum melegueta [Roscoe.] K …

Medicinal plants in traumatic brain injury: Neuroprotective mechanisms revisited

Z Keshavarzi, F Shakeri, GE Barreto, B Bibak… - Biofactors, 2019 - Wiley Online Library
Traumatic brain injury (TBI) is the most prevalent health problem affecting all age groups,
and leads to many secondary problems in other organs especially kidneys, gastrointestinal …

Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Aframomum melegueta Methanolic Seed Extract

SO Onoja, YN Omeh, MI Ezeja… - Journal of tropical …, 2014 - Wiley Online Library
Aframomum melegueta Schum (Zingiberaceae) is a perennial herb widely cultivated for its
valuable seeds in the tropical region of Africa. The present study evaluated the antioxidant …

Antiglycation, antioxidant and toxicological potential of polyphenol extracts of alligator pepper, ginger and nutmeg from Nigeria

MI Kazeem, MA Akanji, RM Hafizur… - Asian Pacific journal of …, 2012 - Elsevier
Objective To evaluate the antioxidant and antiglycation potential of polyphenols from three
spices; alligator pepper, ginger and nutmeg. Methods Polyphenol extracts of these spices …

Anti-inflammatory Activity of Grains of Paradise (Aframomum melegueta Schum) Extract

NM Ilic, M Dey, AA Poulev, S Logendra… - Journal of agricultural …, 2014 - ACS Publications
The ethanolic extract of grains of paradise (Aframomum melegueta Schum, Zingiberaceae)
has been evaluated for inhibitory activity on cyclooxygenase-2 (COX-2) enzyme, in vivo for …

Toxicological evaluation of grains of paradise (Aframomum melegueta)[Roscoe] K. Schum.

N Ilic, BM Schmidt, A Poulev, I Raskin - Journal of ethnopharmacology, 2010 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Grains of Paradise (Aframomum melegueta
[Roscoe] K. Schum.) seeds are used in West Africa as a remedy for variety of ailments such …

Intranasal delivery of tapentadol hydrochloride–loaded chitosan nanoparticles: formulation, characterisation and its in vivo evaluation

A Javia, H Thakkar - Journal of microencapsulation, 2017 - Taylor & Francis
The aim of the present investigation was to formulate tapentadol hydrochloride–loaded
chitosan nanoparticles (CS-NPs) for nose to brain delivery. Chitosan nanoparticles were …

Protective Effect of Aframomum melegueta phenolics Against CCl4-Induced Rat Hepatocytes Damage; Role of Apoptosis and Pro-inflammatory Cytokines inhibition

AM El-Halawany, RSE Dine, NS El Sayed, M Hattori - Scientific reports, 2014 - nature.com
Aframomum melegueta is a commonly used African spice. Through a hepatoprotective
bioassay-guided isolation, the chloroform fraction of A. melegueta seeds yielded one new …

6‐Paradol Acts as a Potential Anti‐obesity Vanilloid from Grains of Paradise

H Hattori, T Mori, T Shibata, M Kita… - Molecular Nutrition & …, 2021 - Wiley Online Library
Scope Grains of Paradise (GOP), the seeds of Aframomum melegueta, has anti‐obesity
effects. However, the mechanisms underlying the effects remain unclear. Methods and …

Analgesic and anti-inflammatory effects of the methanol root extracts of some selected Nigerian medicinal plants

IO Ishola, EO Agbaje, OO Adeyemi… - Pharmaceutical …, 2014 - Taylor & Francis
Abstract Context: The roots of Alafia barteri Oliver (Apocynaceae), Combretum mucronatum
Schumach (Combretaceae) and Capparis thonningii Schum (Capparaceae) are used in …