Colorectal cancer (CRC), ranking as the third most common cancer globally, is associated
with a high death rate. The colon, also known as the large intestine, is the site where …

The gut microbiota is a dynamic community of bacteria distributed in the gastroenteric tract
and changes in response to diseases, diet, use of antibiotics and probiotics, hygiene status …

Silibinin (SBN) is a natural, plant-derived bioactive flavonolignan, possessing wide range of
pharmaceutical activities including anticancer. However, poor aqueous solubility and low …

In the cutting-edge era of developing precision therapeutics, nanoparticles have emerged as
a potent drug delivery system. Altering the size of poorly water-soluble drugs to nanoscale …

Polysaccharide-based drug delivery systems are in high demand due to their
biocompatibility, non-toxicity, and low-cost. In this study, sialic acid receptor targeted 4 …

Fisetin (FST), a natural flavonoid compound derived from various fruits and vegetables,
including apple, strawberry, and onion, demonstrates potential for a wide range of …

Cervical cancer is the fourth most common cancer among women. Despite recent
advancements in diagnostics and therapeutics, this disease is still a formidable challenge to …

Evodiamine (EVO) is a tryptamine indole alkaloid and the main active ingredient in Evodia
rutaecarpa. In recent years, the antitumor, cardioprotective, anti-inflammatory, and anti …

The tumor microenvironment is distinguished from normal tissues, such as the acidic
microenvironment, elevated reactive oxygen species (ROS) levels, and overexpressed …

Owing to high efficacy and safety, natural medicines have found their way into the field of
cancer therapy over the past few decades. However, the effective ingredients of natural …