The inter-relationship between delirium and dementia: the importance of delirium prevention

TG Fong, SK Inouye - Nature Reviews Neurology, 2022 - nature.com
Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …

Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018

L Evered, B Silbert, DS Knopman, DA Scott… - …, 2018 - pubs.asahq.org
Cognitive change affecting patients after anaesthesia and surgery has been recognised for
more than 100 yr. Research into cognitive change after anaesthesia and surgery …

[HTML][HTML] Anaesthetic depth and delirium after major surgery: a randomised clinical trial

LA Evered, MTV Chan, R Han, MHM Chu… - British journal of …, 2021 - Elsevier
Background Postoperative delirium is a serious complication of surgery associated with
prolonged hospitalisation, long-term cognitive decline, and mortality. This study aimed to …

Association of delirium with long-term cognitive decline: a meta-analysis

TE Goldberg, C Chen, Y Wang, E Jung… - JAMA …, 2020 - jamanetwork.com
Importance Delirium is associated with increased hospital costs, health care complications,
and increased mortality. Long-term consequences of delirium on cognition have not been …

Delirium in hospitalized older adults

ER Marcantonio - New England Journal of Medicine, 2017 - Mass Medical Soc
Key Clinical Points Delirium in Hospitalized Older Adults Delirium is an acute confusional
state that is extremely common among hospitalized elders and is strongly associated with …

One-year medicare costs associated with delirium in older patients undergoing major elective surgery

RY Gou, TT Hshieh, ER Marcantonio, Z Cooper… - JAMA …, 2021 - jamanetwork.com
Importance Delirium is a common, serious, and potentially preventable problem for older
adults, associated with adverse outcomes. Coupled with its preventable nature, these …

Delirium in older persons: advances in diagnosis and treatment

ES Oh, TG Fong, TT Hshieh, SK Inouye - Jama, 2017 - jamanetwork.com
Importance Delirium is defined as an acute disorder of attention and cognition. It is a
common, serious, and often fatal condition among older patients. Although often …

American society for enhanced recovery and perioperative quality initiative joint consensus statement on postoperative delirium prevention

CG Hughes, CS Boncyk, DJ Culley… - Anesthesia & …, 2020 - journals.lww.com
Postoperative delirium is a geriatric syndrome that manifests as changes in cognition,
attention, and levels of consciousness after surgery. It occurs in up to 50% of patients after …

Neuroinflammation after surgery: from mechanisms to therapeutic targets

T Yang, R Velagapudi, N Terrando - Nature immunology, 2020 - nature.com
Injury is a key driver of inflammation, a critical yet necessary response involving several
mediators that is aimed at restoring tissue homeostasis. Inflammation in the central nervous …

[HTML][HTML] Postoperative delirium: perioperative assessment, risk reduction, and management

Z Jin, J Hu, D Ma - British journal of anaesthesia, 2020 - Elsevier
Postoperative delirium is a relatively common and serious complication. It increases hospital
stay by 2–3 days and is associated with a 30-day mortality of 7–10%. It is most prevalent in …