Targeting Wnt/β-catenin pathway for developing therapies for hair loss

BY Choi - International journal of molecular sciences, 2020 - mdpi.com
Persistent hair loss is a major cause of psychological distress and compromised quality of
life in millions of people worldwide. Remarkable progress has been made in understanding …

Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth

A Madaan, R Verma, AT Singh… - International journal of …, 2018 - Wiley Online Library
Hair disorders such as hair loss (alopecia) and androgen dependent, excessive hair growth
(hirsutism, hypertrichosis) may impact the social and psychological well‐being of an …

Mesenchymal stem cell secretome for dermatology application: a review

RH Damayanti, T Rusdiana… - Clinical, cosmetic and …, 2021 - Taylor & Francis
Secretome, also known as conditioned medium, is a secreted molecule from mesenchymal
stem cells (MSCs) that has a variety of biological activities that can be used in various …

Potential of colostrum-derived exosomes for promoting hair regeneration through the transition from telogen to anagen phase

H Kim, Y Jang, EH Kim, H Jang, H Cho… - Frontiers in Cell and …, 2022 - frontiersin.org
Human hair dermal papillary (DP) cells comprising mesenchymal stem cells in hair follicles
contribute critically to hair growth and cycle regulation. The transition of hair follicles from …

Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia

A Premanand, B Reena Rajkumari - Archives of dermatological research, 2018 - Springer
Androgenetic alopecia (AGA) is a dermatological disorder of scalp hair loss characterized by
a progressive miniaturization of hair follicles with shortened anagen phase leading to a …

Hair growth: focus on herbal therapeutic agent

S Patel, V Sharma, NS Chauhan… - Current drug …, 2015 - ingentaconnect.com
This review presents an overview on plants identified to possess hair growth activity in
various ethno-botanical studies and surveys of tradition medicinal plants. It also highlights …

The molecular mechanism of natural products activating Wnt/β-catenin signaling pathway for improving hair loss

DW Shin - Life, 2022 - mdpi.com
Hair loss, or alopecia, is a dermatological disorder that causes psychological stress and
poor quality of life. Drug-based therapeutics such as finasteride and minoxidil have been …

KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis

YC Ryu, DH Lee, J Shim, J Park, YR Kim… - British journal of …, 2021 - Wiley Online Library
Background and Purpose The promotion of hair regeneration and growth heavily depends
on the activation of Wnt/β‐catenin signalling in the hair follicle, including dermal papilla …

Phytochemicals: potential therapeutic modulators of radiation induced signaling pathways

BP Jit, B Pradhan, R Dash, PP Bhuyan, C Behera… - Antioxidants, 2021 - mdpi.com
Ionizing radiation results in extensive damage to biological systems. The massive amount of
ionizing radiation from nuclear accidents, radiation therapy (RT), space exploration, and the …

Mechanism of action of herbs and their active constituents used in hair loss treatment

A Herman, AP Herman - Fitoterapia, 2016 - Elsevier
This article discusses the mechanisms via topically applied products containing herbs and
their active constituents affect the hair growth process. It was reported that the mechanisms …