Cholesterol: An important actor on the cancer immune scene

H Halimi, S Farjadian - Frontiers in Immunology, 2022 - frontiersin.org
Based on the structural and signaling roles of cholesterol, which are necessary for immune
cell activity, high concentrations of cholesterol and its metabolites not only trigger malignant …

Advances in natural killer cell therapies for breast cancer

SZF Kiaei, A Nouralishahi… - … and Cell Biology, 2023 - Wiley Online Library
Breast cancer (BC) is the most common cause of cancer death in women. According to the
American Cancer Society's yearly cancer statistics, BC constituted almost 15% of all the …

KIR-HLA gene diversities and susceptibility to lung cancer

M Hematian Larki, E Ashouri, S Barani… - Scientific Reports, 2022 - nature.com
Killer-cell immunoglobulin-like receptors (KIR) are essential for acquiring natural killer (NK)
cell effector function, which is modulated by a balance between the net input of signals …

Individualized constellation of killer cell immunoglobulin-like receptors and cognate HLA class I ligands that controls natural killer cell antiviral immunity predisposes …

S Maruthamuthu, K Rajalingam, N Kaur… - Frontiers in …, 2022 - frontiersin.org
Background: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection
causes coronavirus disease-2019 (COVID-19) in some individuals, while the majority …

[HTML][HTML] Polymorphism of HLA and Susceptibility of Breast Cancer

S Aboulaghras, A Khalid, HA Makeen… - Frontiers in Bioscience …, 2024 - imrpress.com
Breast cancer (BC) is the second most common malignancy in the world. Numerous studies
have demonstrated the association between human leukocyte antigen (HLA) and cancer …

Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer

Z Shiravani, K Mirshekari, MH Larki, N Shafiee… - Journal of Reproductive …, 2024 - Elsevier
Endometrial cancer (EC) constitutes more than half of all genital cancers in women, with an
increasing incidence in different countries. Natural killer cells (NK cells) are kinds of innate …

Impact of HLA Class I Antigen, Killer Inhibitory Receptor, and FCGR3A Genotypes on Breast Cancer Susceptibility and Tumor Stage

A Canossi, A Aureli, T Del Beato… - Current Molecular …, 2024 - ingentaconnect.com
Background: The identification in breast cancer (BC) of novel genetic biomarkers regulating
natural killer (NK) cell function, including the HLA, KIR, and CD16A (FCGR3A), may be still a …

Harnessing Natural Killer Cells for Cancer Therapy

R Rajalingam - Handbook of Cancer and Immunology, 2025 - Springer
Natural killer (NK) cells are large granular innate lymphocytes crucial for the early control of
oncogenic transformation and viral infections. Although initially defined as common cytotoxic …

The impact of killer cell immunoglobulin-like receptor (KIR) genes and human leukocyte antigen (HLA) class I ligands on predisposition or protection against prostate …

MR Zamir, A Ariafar, A Ghaderi, A Amirzargar - Immunobiology, 2023 - Elsevier
Natural killer (NK) cell development largely depends on killer cell immunoglobulin-like
receptors (KIRs) and human leukocyte antigen (HLA) class I ligands. In the current study, we …

[引用][C] Papel de las células Natural Killer en la susceptibilidad y el pronóstico de la COVID-19

M Moreno Hernández - Proyecto de investigación:, 2024 - Universidad de Murcia