The tissue microenvironment regulates mammary gland development and tissue
homeostasis through soluble, insoluble and cellular cues that operate within the three …

Polymeric nanofibers have potential as tissue engineering scaffolds, as they mimic the
nanoscale properties and structural characteristics of native extracellular matrix (ECM) …

Arteries exhibit a remarkable ability to adapt to diverse genetic defects and sustained
alterations in mechanical loading. For example, changes in blood flow induced wall shear …

A new compliant scaffold suitable for small-diameter vascular grafts has been developed
that promotes strong attachment of endothelial cells. Composite scaffolds were produced by …

We have developed a family of synthetic biodegradable polymers that are composed of
structural units endogenous to the human metabolism, designated poly (polyol …

Abstract Poly (glycerol sebacate)(PGS), a promising scaffold material for soft tissue
engineering applications, is a soft, tough elastomer with excellent biocompatibility. However …

Mechanical conditioning represents a potential means to enhance the biochemical and
biomechanical properties of tissue engineered vascular grafts (TEVGs). A pulsatile flow …

This review will focus on two elements that are essential for functional arterial regeneration
in vitro: the mechanical environment and the bioreactors used for tissue growth. The …

Much of our understanding of vascular mechanotransduction has come from studies using
either cell culture or in vivo animal models, but the recent success of organ culture systems …

Biomechanics relates the function of a physiological system to its structure. The objective of
biomechanics is to deduce the function of a system from its geometry, material properties …