Obesity is a major risk factor for several metabolic diseases, including type 2 diabetes,
hyperlipidemia, cardiovascular diseases, and brain disorders. Growing evidence suggests …

Heart failure (HF) is one of the leading causes of death, affecting more than 20 million
people worldwide. A vast array of pathophysiological and molecular events contributes to …

A high‐fat diet (HFD) has been associated with heart failure and arrhythmias; however, the
molecular mechanisms underlying these associations are poorly understood. The …

High-mobility group box 2 (HMGB2) is an abundant, chromatin-associated protein that plays
an essential role in the regulation of transcription, cell proliferation, differentiation, and …

Obesity has been demonstrated to be linked to atrial fibrillation (AF) with atrial enlargement
and tissue fibrosis. Long-term high calorie intake is the main reason for the prevalence of …

Maternal high-fat diet (HFD) during pregnancy is linked to cardiovascular diseases in
postnatal life. The current study tested the hypothesis that maternal HFD causes myocardial …

High-calorie diet-induced obesity leads to cardiomyocyte dysfunction and apoptosis.
Impaired regulation of epididymal fat content in obese patients has been known to increase …

Abstract Background A Nox2 containing NADPH oxidase (Nox2) is involved in the global
oxidative stress found in dietary obesity and metabolic disorders. However, the effects of …

Background Over a third of reproductive-age women in the USA are obese, and the
prevalence of cardiovascular disease (CVD) is rising in premenopausal women. Cardiac …

The aim of the study was to characterize if the development of cardiac hypertrophy (CH)
caused by severe left ventricle (LV) volume overload (VO) from chronic aortic valve …