RONS and oxidative stress: An overview of basic concepts

AK Aranda-Rivera, A Cruz-Gregorio… - Oxygen, 2022 - mdpi.com
Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …

Disorders of human coenzyme Q10 metabolism: an overview

I Hargreaves, RA Heaton, D Mantle - International journal of molecular …, 2020 - mdpi.com
Coenzyme Q10 (CoQ10) has a number of vital functions in all cells, both mitochondrial and
extramitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation …

Quinones as neuroprotective agents

Á Cores, N Carmona-Zafra, J Clerigué, M Villacampa… - Antioxidants, 2023 - mdpi.com
Quinones can in principle be viewed as a double-edged sword in the treatment of
neurodegenerative diseases, since they are often cytoprotective but can also be cytotoxic …

[HTML][HTML] Coenzyme Q10 supplementation–In ageing and disease

J Aaseth, J Alexander, U Alehagen - Mechanisms of Ageing and …, 2021 - Elsevier
Abstract Coenzyme Q 10 (CoQ 10) is an essential component of the mitochondrial electron
transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All cells …

Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space …

X Gómez, S Sanon, K Zambrano, S Asquel… - npj …, 2021 - nature.com
Exposure to microgravity and ionizing radiation during spaceflight missions causes
excessive reactive oxygen species (ROS) production that contributes to cellular stress and …

The neuroprotective role of coenzyme Q10 against lead acetate-induced neurotoxicity is mediated by antioxidant, anti-inflammatory and anti-apoptotic activities

AO S. Yousef, A A. Fahad, AE Abdel Moneim… - International journal of …, 2019 - mdpi.com
Heavy metal exposure, in lead (Pb) particularly, is associated with severe neuronal
impairment though oxidative stress mediated by reactive oxygen species, and antioxidants …

[HTML][HTML] Complex II ambiguities—FADH2 in the electron transfer system

E Gnaiger - Journal of Biological Chemistry, 2024 - Elsevier
The prevailing notion that reduced cofactors NADH and FADH 2 transfer electrons from the
tricarboxylic acid cycle to the mitochondrial electron transfer system creates ambiguities …

Does coenzyme Q10 supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta …

P Florou, P Anagnostis, P Theocharis… - Journal of assisted …, 2020 - Springer
Objective Increased oxidative stress has been identified as a pathogenetic mechanism in
female infertility. However, the effect of specific antioxidants, such as coenzyme Q 10 (CoQ …

Nutritional factors and physical frailty: Highlighting the role of functional nutrients in the prevention and treatment

R Ziaei, F Shahdadian, M Bagherniya, S Karav… - Ageing Research …, 2024 - Elsevier
Physical frailty, an age-related decline in the physiological capacity and function of various
organs, is associated with higher vulnerability to unfavorable health outcomes. The …

Combined Supplementation of Coenzyme Q10 and Other Nutrients in Specific Medical Conditions

T Tippairote, G Bjørklund, A Gasmi, Y Semenova… - Nutrients, 2022 - mdpi.com
Coenzyme Q10 (CoQ10) is a compound with a crucial role in mitochondrial bioenergetics
and membrane antioxidant protection. Despite the ubiquitous endogenous biosynthesis …