Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary …

MN Diringer, TP Bleck, J Claude Hemphill, D Menon… - Neurocritical care, 2011 - Springer
Subarachnoid hemorrhage (SAH) is an acute cerebrovascular event which can have
devastating effects on the central nervous system as well as a profound impact on several …

Early brain injury, an evolving frontier in subarachnoid hemorrhage research

M Fujii, J Yan, WB Rolland, Y Soejima, B Caner… - Translational stroke …, 2013 - Springer
Subarachnoid hemorrhage (SAH), predominantly caused by a ruptured aneurysm, is a
devastating neurological disease that has a morbidity and mortality rate higher than 50 …

Guidelines for the neurocritical care management of aneurysmal subarachnoid hemorrhage

MM Treggiari, AA Rabinstein, KM Busl, MM Caylor… - Neurocritical care, 2023 - Springer
Background The neurointensive care management of patients with aneurysmal
subarachnoid hemorrhage (aSAH) is one of the most critical components contributing to …

Delayed cerebral ischaemia after subarachnoid haemorrhage: looking beyond vasospasm

MJ Rowland, G Hadjipavlou, M Kelly… - British journal of …, 2012 - academic.oup.com
Despite improvements in the clinical management of aneurysmal subarachnoid
haemorrhage over the last decade, delayed cerebral ischaemia (DCI) remains the single …

The pathophysiology and treatment of delayed cerebral ischaemia following subarachnoid haemorrhage

KP Budohoski, M Guilfoyle, A Helmy… - Journal of Neurology …, 2014 - jnnp.bmj.com
Cerebral vasospasm has traditionally been regarded as an important cause of delayed
cerebral ischaemia (DCI) which occurs after aneurysmal subarachnoid haemorrhage, and …

Systemic inflammation in hemorrhagic strokes–A novel neurological sign and therapeutic target?

AR Saand, F Yu, J Chen… - Journal of Cerebral Blood …, 2019 - journals.sagepub.com
Growing evidences suggest that stroke is a systemic disease affecting many organ systems
beyond the brain. Stroke-related systemic inflammatory response and immune …

Simvastatin in aneurysmal subarachnoid haemorrhage (STASH): a multicentre randomised phase 3 trial

PJ Kirkpatrick, CL Turner, C Smith… - The Lancet …, 2014 - thelancet.com
Background The benefit of statins in patients with acute aneurysmal subarachnoid
haemorrhage is unclear. We aimed to determine whether simvastatin 40 mg could improve …

Clinical and experimental aspects of aneurysmal subarachnoid hemorrhage

BJ Daou, S Koduri, BG Thompson… - CNS neuroscience & …, 2019 - Wiley Online Library
Aneurysmal subarachnoid hemorrhage (aSAH) continues to be associated with significant
morbidity and mortality despite advances in care and aneurysm treatment strategies …

Effect of pharmaceutical treatment on vasospasm, delayed cerebral ischemia, and clinical outcome in patients with aneurysmal subarachnoid hemorrhage: a …

N Etminan, MDI Vergouwen… - Journal of cerebral …, 2011 - journals.sagepub.com
As it is often assumed that delayed cerebral ischemia (DCI) after subarachnoid hemorrhage
(SAH) is caused by vasospasm, clinical trials often focus on prevention of vasospasm with …

Prophylactic therapies for morbidity and mortality after aneurysmal subarachnoid hemorrhage: a systematic review and network meta-analysis of randomized trials

M Dayyani, B Sadeghirad, JC Grotta, S Zabihyan… - Stroke, 2022 - Am Heart Assoc
Background: Aneurysmal subarachnoid hemorrhage (aSAH) is associated with high
mortality and morbidity. We aimed to determine the relative benefits of pharmacological …