Mechanisms of germ cell specification across the metazoans: epigenesis and preformation

CG Extavour, M Akam - 2003 - journals.biologists.com
Germ cells play a unique role in gamete production, heredity and evolution. Therefore, to
understand the mechanisms that specify germ cells is a central challenge in developmental …

The origin of pattern and polarity in the Drosophila embryo

D St Johnston, C Nüsslein-Volhard - cell, 1992 - Elsevier
'The development of a multicellular organism from a single egg cell requires both the
determination of many cell types and the organization of these cells into an elaborate pattern …

Direct observation of translational activation by a ribonucleoprotein granule

R Chen, W Stainier, J Dufourt, M Lagha… - Nature Cell …, 2024 - nature.com
Biomolecular condensates organize biochemical processes at the subcellular level and can
provide spatiotemporal regulation within a cell. Among these, ribonucleoprotein (RNP) …

[HTML][HTML] Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels

M Kato, TW Han, S Xie, K Shi, X Du, LC Wu, H Mirzaei… - Cell, 2012 - cell.com
Eukaryotic cells contain assemblies of RNAs and proteins termed RNA granules. Many
proteins within these bodies contain KH or RRM RNA-binding domains as well as low …

A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary

H Lin, AC Spradling - Development, 1997 - journals.biologists.com
Germline stem cells play a pivotal role in gametogenesis; yet little is known about how they
are formed, how they divide to self-renew, and how these processes are genetically …

Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo

C Rouget, C Papin, A Boureux, AC Meunier, B Franco… - Nature, 2010 - nature.com
Abstract Piwi-associated RNAs (piRNAs), a specific class of 24-to 30-nucleotide-long RNAs
produced by the Piwi-type of Argonaute proteins, have a specific germline function in …

Induction of germ cell formation by oskar

A Ephrussi, R Lehmann - Nature, 1992 - nature.com
The oskar gene directs germ plasm assembly and controls the number of germ cell
precursors formed at the posterior pole of the Drosophila embryo. Mislocalization of oskar …

Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast

AP Gerber, D Herschlag, PO Brown - PLoS biology, 2004 - journals.plos.org
Genes encoding RNA-binding proteins are diverse and abundant in eukaryotic genomes.
Although some have been shown to have roles in post-transcriptional regulation of the …

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos

A Ephrussi, LK Dickinson, R Lehmann - Cell, 1991 - cell.com
Summary oskar is one of seven Drosophila maternal-effect genes that are necessary for
germline and abdomen formation. We have cloned oskar and show that oskar RNA is …

[图书][B] The insect ovary: ultrastructure, previtellogenic growth and evolution

J Büning - 1994 - books.google.com
This book will give an overview of insect ovaries, showing the diversities and the common
traits in egg growth processes. The idea to write this book developed while looking at the …