MmpL3 inhibition: a new approach to treat nontuberculous mycobacterial infections
JP Sethiya, MA Sowards, M Jackson… - International journal of …, 2020 - mdpi.com
Outside of Mycobacterium tuberculosis and Mycobacterium leprae, nontuberculous
mycobacteria (NTM) are environmental mycobacteria (> 190 species) and are classified as …
mycobacteria (NTM) are environmental mycobacteria (> 190 species) and are classified as …
Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes
D Evangelopoulos, GA Prosser, A Rodgers… - Nature …, 2019 - nature.com
Drug resistant infections represent one of the most challenging medical problems of our
time. d-cycloserine is an antibiotic used for six decades without significant appearance and …
time. d-cycloserine is an antibiotic used for six decades without significant appearance and …
Prediction of drug resistance by Sanger sequencing of Mycobacterium tuberculosis complex strains isolated from multidrug resistant tuberculosis suspect patients in …
Background Ethiopia is one of the high multidrug-resistant tuberculosis (MDR-TB) burden
countries. However, phenotypic drug susceptibility testing can take several weeks due to the …
countries. However, phenotypic drug susceptibility testing can take several weeks due to the …
Investigate natural product indolmycin and the synthetically improved analogue toward antimycobacterial agents
Y Yang, Y Xu, Y Yue, H Wang, Y Cui, M Pan… - ACS Chemical …, 2021 - ACS Publications
Indolmycin (IND) is a microbial natural product that selectively inhibits bacterial tryptophanyl-
tRNA synthetase (TrpRS). The tryptophan biosynthesis pathway was recently shown to be …
tRNA synthetase (TrpRS). The tryptophan biosynthesis pathway was recently shown to be …
[HTML][HTML] Resistance Sniffer: An online tool for prediction of drug resistance patterns of Mycobacterium tuberculosis isolates using next generation sequencing data
D Muzondiwa, A Mutshembele, RE Pierneef… - International Journal of …, 2020 - Elsevier
The effective control of multidrug resistant tuberculosis (MDR-TB) relies upon the timely
diagnosis and correct treatment of all tuberculosis cases. Whole genome sequencing (WGS) …
diagnosis and correct treatment of all tuberculosis cases. Whole genome sequencing (WGS) …
Whole-Genome Sequence-Based Characterization of Pre-XDR M. tuberculosis Clinical Isolates Collected in Kazakhstan
A Daniyarov, A Akhmetova, S Rakhimova, Z Abilova… - Diagnostics, 2023 - mdpi.com
Background: Kazakhstan has a high burden of multidrug-resistant tuberculosis in the Central
Asian region. This study aimed to perform genomic characterization of Mycobacterium …
Asian region. This study aimed to perform genomic characterization of Mycobacterium …
The effect of iodine-containing nano-micelles, FS-1, on antibiotic resistance, gene expression and epigenetic modifications in the genome of multidrug resistant MRSA …
ON Reva, IS Korotetskiy, M Joubert, SV Shilov… - Frontiers in …, 2020 - frontiersin.org
Application of supplementary drugs which increase susceptibility of pathogenic bacteria to
antibiotics is a promising yet unexplored approach to overcome the global problem of …
antibiotics is a promising yet unexplored approach to overcome the global problem of …
[HTML][HTML] Transcriptomic analysis of sub-MIC Eugenol exposition on antibiotic resistance profile in Multidrug Resistant Enterococcus faecalis E9. 8
NC Gómez, J Manetsberger, S Castillo-Gutiérrez… - Microbiological …, 2025 - Elsevier
The spread of multidrug-resistant (MDR) bacteria and their resistance genes along the food
chain and the environment has become a global threat aggravated by incorrect disinfection …
chain and the environment has become a global threat aggravated by incorrect disinfection …
Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets
Mycobacterium tuberculosis is a known human pathogen that causes the airborne infectious
disease tuberculosis (TB). Every year TB infects millions of people worldwide. The …
disease tuberculosis (TB). Every year TB infects millions of people worldwide. The …
Universal Lineage-Independent Markers of Multidrug Resistance in Mycobacterium tuberculosis
(1) Background: This study was aimed to identify universal genetic markers of multidrug
resistance (MDR) in Mycobacterium tuberculosis (Mtb) and establish statistical associations …
resistance (MDR) in Mycobacterium tuberculosis (Mtb) and establish statistical associations …