Implants are widely used for orthopaedic applications such as fixing fractures, repairing non-
unions, obtaining a joint arthrodesis, total joint arthroplasty, spinal reconstruction, and soft …

Since various interactions among cells, surrounding tissues and implanted biomaterials
always occur at their interfaces, the surface properties of potential implants appear to be of …

Titanium implants are widely used in the orthopedic and dentistry fields for many decades,
for joint arthroplasties, spinal and maxillofacial reconstructions, and dental prostheses …

Calcium phosphate is the inorganic mineral of hard tissues such as bone and teeth. Due to
their similarities to the natural bone, calcium phosphates are highly biocompatible and …

A The present overview describes various production techniques for biocompatible calcium
orthophosphate (abbreviated as CaPO4) deposits (coatings, films and layers) on the …

Translation of scaffold-based bone tissue engineering (BTE) therapies to clinical use
remains, bluntly, a failure. This dearth of translated tissue engineering therapies (including …

Development of synthetic biomaterials imbued with inorganic and organic characteristics of
natural bone that are capable of promoting effective bone tissue regeneration is an ongoing …

The commercial success of tissue engineering products requires efficacy, cost effectiveness,
and the possibility of scaleup. Advances in tissue engineering require increased …

Implant-associated infections are among the most serious post-surgical complications of
medical device implants, including prosthetic joints (eg, hip, knee and shoulder) and fracture …

Despite the high innate regenerative capacity of bone, large osseous defects fail to heal and
remain a clinical challenge. Healing such defects requires the formation of large amounts of …