Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

Despite the generally held view that alcohol is an unspecific pharmacological agent, recent
molecular pharmacology studies demonstrated that alcohol has only a few known primary …

Alcohol use disorder (AUD) encompasses the dysregulation of multiple brain circuits
involved in executive function leading to excessive consumption of alcohol, despite negative …

Background The “classic” endocannabinoid (eCB) system includes the cannabinoid
receptors CB1 and CB2, the eCB ligands anandamide (AEA) and 2-arachidonoylglycerol (2 …

Recent prospective studies provided evidence that higher adherence to a Mediterranean-
type diet could be associated with slower cognitive decline, reduced risk of progression from …

The endogenous cannabinoid system is an important regulatory system involved in
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …

The endocannabinoids anandamide (arachidonoyl ethanolamide, AEA) and 2-arachidonoyl
glycerol (2AG) are physiologically occurring, biologically active compounds on CB1 and …

Endocannabinoids play an important role in a diverse range of neurophysiological
processes including neural development, neuroimmune function, synaptic plasticity, pain …

Over the past fifty years a significant body of evidence has been compiled suggesting an
interaction between the endocannabinoid (EC) system and alcohol dependence. However …

Anandamide and the other N-acylethanolamines, eg oleoylethanolamide (OEA),
palmitoylethanolamide (PEA), and linoleoylethanolamide (LEA), may be formed by several …