Scientific rationale for developing potent RBD-based vaccines targeting COVID-19

H Kleanthous, JM Silverman, KW Makar, IK Yoon… - npj Vaccines, 2021 - nature.com
Vaccination of the global population against COVID-19 is a great scientific, logistical, and
moral challenge. Despite the rapid development and authorization of several full-length …

Functionalizing ferritin nanoparticles for vaccine development

MQ Rodrigues, PM Alves, A Roldão - Pharmaceutics, 2021 - mdpi.com
In the last decade, the interest in ferritin-based vaccines has been increasing due to their
safety and immunogenicity. Candidates against a wide range of pathogens are now on …

Tumor-targeted nano-delivery system of therapeutic RNA

M Wang, J Zhao, H Jiang, X Wang - Materials horizons, 2022 - pubs.rsc.org
The birth of RNAi technology has pioneered actionability at the molecular level. Compared
to DNA, RNA is less stable and therefore requires more demanding delivery vehicles. With …

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of Dabie bandavirus in aged ferrets

D Kim, E Kim, S Kim, Y Chung, CJ Lai, I Cha, SD Cho… - Mbio, 2023 - Am Soc Microbiol
Dabie bandavirus (DBV), previously known as severe fever with thrombocytopenia
syndrome (SFTS) virus, induces a characteristic thrombocytopenia with a mortality rate …

[HTML][HTML] Coronavirus spike protein-based vaccines. Vaccine delivery systems

AM Asrorov, MS Ayubov, B Tu, M Shi, H Wang… - Medicine in Drug …, 2024 - Elsevier
Spike protein has been established as one of the molecules playing a pivotal role in
coronavirus infection. On its bases, several vaccines have been developed, passed …

An S1 subunit vaccine and combination adjuvant (COVAC-1) elicits robust protection against SARS-CoV-2 challenge in African green monkeys

L Garnett, KN Tran, M Chan, K Tierney, Z Schiffman… - bioRxiv, 2022 - biorxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent responsible for
the ongoing global pandemic. With over 500 million cases and more than 6 million deaths …

Investigating the Fundamental Molecular Interactions Responsible for Polymer Mucoadhesion

JD Watchorn - 2023 - search.proquest.com
Polymer-protein interactions are fundamental to the success of drug delivery vehicles, as
they dictate their biological fate. There are many examples of these protein-polymer …

[PDF][PDF] FACULTAD DE ODONTOLOGÍA

ADEDRCON UN - 2005 - ru.dgb.unam.mx
La realización de este trabajo es la culminación de la primera etapa de mi formación
profesional, empleado los conocimientos adquiridos durante mis estudios de pregrado y en …