A disruption of the crucial balance between regulatory T-cells (Tregs) and Th17-cells was
recently implicated in various autoimmune disorders. Tregs are responsible for the …

Interleukin 17A (IL-17A) is one of the currently known six members of the IL-17 cytokine
family and is implicated in immune responses to infectious pathogens and in the …

Background Bimekizumab is a monoclonal IgG1 antibody that selectively inhibits interleukin
(IL)-17F in addition to IL-17A. This study investigated the efficacy and safety of bimekizumab …

Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

Background The present review is part of the ESCMID Study Group for Infections in
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …

Eleven biologic drugs are currently approved for psoriasis management. Real‐life studies
are needed to guide clinicians in choosing a tailored‐tail therapy. The aim of our …

UV-based phototherapy (including psoralen plus UVA (PUVA), UVB and UVA1) has a long,
successful history in the management of numerous cutaneous disorders. Photoresponsive …

Serum and plasma contain abundant biological information that reflect the body's
physiological and pathological conditions and are therefore a valuable sample type for …

Insights into the pathophysiology of autoimmune inflammatory diseases including psoriasis
have advanced considerably in recent years, and in parallel, so too have the available …

Psoriasis is a chronic inflammatory skin condition affecting diverse racial/ethnic groups
throughout the world. Large population-based studies suggest that psoriasis occurs most …