Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …

Background Head and neck squamous cell cancer (HNSCC) is the most common cancer
associated with chewing tobacco, in the world. As this is divided in to sites and subsites, it …

In solid tumours, cancer cells that undergo epithelial mesenchymal transition (EMT) express
characteristic gene expression signatures that promote invasive migration as well as the …

The cytolinker and scaffolding protein, plectin, has emerged as a potent driver of malignant
hallmarks in many human cancers due to its involvement in various cellular activities …

Fascin actin-bundling protein 1 (FSCN1) is an actin-bundling protein that is capable of
inducing membrane protrusions and plays critical roles in cell migration, motility, adhesion …

Serrated adenocarcinoma (SAC) is more invasive, has worse outcomes than conventional
colorectal carcinoma (CRC), and is characterized by frequent resistance to anti-epidermal …

Simple Summary Colorectal cancer (CRC) is the third leading cause of cancer-related
deaths worldwide. Serrated adenocarcinoma (SAC) has been recently recognized by the …

Aberrant expression of certain microRNAs (miRNAs) has been implicated in cancers as a
promising druggable target due to the fact that a modulation of the deregulated single …

The plectin gene can encode a cytoskeletal linking protein, plectin, known for its interaction
with three critical components of the cellular cytoskeleton: intermediate filaments …

Metastasis is the primary cause of mortality and morbidity among cancer patients and
accounts for about 90% of cancer deaths. The most common types of treatment for cancer …