The many alternative faces of macrophage activation

DA Hume - Frontiers in immunology, 2015 - frontiersin.org
Monocytes and macrophages provide the first line of defense against pathogens. They also
initiate acquired immunity by processing and presenting antigens and provide the …

From RNA-seq reads to differential expression results

A Oshlack, MD Robinson, MD Young - Genome biology, 2010 - Springer
From RNA-seq reads to differential expression results | Genome Biology Skip to main content
SpringerLink Account Menu Find a journal Publish with us Track your research Search Cart …

The mouse microbiome is required for sex-specific diurnal rhythms of gene expression and metabolism

BD Weger, C Gobet, J Yeung, E Martin, S Jimenez… - Cell metabolism, 2019 - cell.com
The circadian clock and associated feeding rhythms have a profound impact on metabolism
and the gut microbiome. To what extent microbiota reciprocally affect daily rhythms of …

A scaling normalization method for differential expression analysis of RNA-seq data

MD Robinson, A Oshlack - Genome biology, 2010 - Springer
The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq
is likely to become the platform of choice for interrogating steady state RNA. In order to …

[HTML][HTML] Multiomic atlas with functional stratification and developmental dynamics of zebrafish cis-regulatory elements

D Baranasic, M Hörtenhuber, PJ Balwierz, T Zehnder… - Nature …, 2022 - nature.com
Zebrafish, a popular organism for studying embryonic development and for modeling human
diseases, has so far lacked a systematic functional annotation program akin to those in other …

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains

BP Berman, DJ Weisenberger, JF Aman, T Hinoue… - Nature …, 2012 - nature.com
Extensive changes in DNA methylation are common in cancer and may contribute to
oncogenesis through transcriptional silencing of tumor-suppressor genes. Genome-scale …

RNA-Seq Atlas of Glycine max: A guide to the soybean transcriptome

AJ Severin, JL Woody, YT Bolon, B Joseph, BW Diers… - BMC plant biology, 2010 - Springer
Background Next generation sequencing is transforming our understanding of
transcriptomes. It can determine the expression level of transcripts with a dynamic range of …

ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs

PJ Balwierz, M Pachkov, P Arnold, AJ Gruber… - Genome …, 2014 - genome.cshlp.org
Accurate reconstruction of the regulatory networks that control gene expression is one of the
key current challenges in molecular biology. Although gene expression and chromatin state …

Corruption of the Pearson correlation coefficient by measurement error and its estimation, bias, and correction under different error models

E Saccenti, MHWB Hendriks, AK Smilde - Scientific reports, 2020 - nature.com
Correlation coefficients are abundantly used in the life sciences. Their use can be limited to
simple exploratory analysis or to construct association networks for visualization but they are …

Statistical design and analysis of RNA sequencing data

PL Auer, RW Doerge - Genetics, 2010 - academic.oup.com
Next-generation sequencing technologies are quickly becoming the preferred approach for
characterizing and quantifying entire genomes. Even though data produced from these …