Alkyl cinnamates as regulator for the C1 domain of protein kinase C isoforms
The protein kinase C (PKC) family of serine/threonine kinases is an attractive drug target for
the treatment of cancer and other diseases. Natural product curcumin is known to interact …
the treatment of cancer and other diseases. Natural product curcumin is known to interact …
Molecular basis for failure of “atypical” C1 domain of Vav1 to bind diacylglycerol/phorbol ester
T Geczy, ML Peach, S El Kazzouli, DM Sigano… - Journal of Biological …, 2012 - ASBMB
C1 domains, the recognition motif of the second messenger diacylglycerol and of the
phorbol esters, are classified as typical (ligand-responsive) or atypical (not ligand …
phorbol esters, are classified as typical (ligand-responsive) or atypical (not ligand …
[图书][B] The Ups and Downs in Drug Design: Adventures in Medicinal Chemistry
VE Marquez - 2021 - taylorfrancis.com
The Ups and Downs in Drug Design: Adventures in Medicinal Chemistry highlights the
necessity for an integrative approach in medicinal chemistry and chemical biology. As …
necessity for an integrative approach in medicinal chemistry and chemical biology. As …