Modern medical management of spinal cord injury

M Karsy, G Hawryluk - Current Neurology and Neuroscience Reports, 2019 - Springer
Abstract Purpose of Review Spinal cord injury (SCI) shows an incidence of 10.4–83
cases/million/year globally and remains a significant source of morbidity and cost to society …

Immune response following traumatic spinal cord injury: Pathophysiology and therapies

RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

Predicting outcomes after spinal cord injury

W Chay, S Kirshblum - Physical Medicine and Rehabilitation …, 2020 - pmr.theclinics.com
Jane Doe is a 66-year-old woman who was involved in a motor vehicle crash where she
sustained a T6 burst fracture. She underwent T5-7 laminectomy and posterior spinal fusion …

[HTML][HTML] “Time is spine”: the importance of early intervention for traumatic spinal cord injury

CS Ahuja, JH Badhiwala, MG Fehlings - Spinal Cord, 2020 - nature.com
Traumatic spinal cord injuries (SCI) have devastating lifelong sequelae for affected
individuals, caregivers, and society. Modest improvements in sensorimotor function can …

Early surgery for traumatic spinal cord injury: where are we now?

JR Wilson, CD Witiw, J Badhiwala… - Global spine …, 2020 - journals.sagepub.com
Study Design: Narrative review. Objective: There is a strong biological rationale to perform
early decompression after traumatic spinal cord injury (SCI). With an enlarging clinical …

Efficacy of ultra-early (< 12 h), early (12–24 h), and late (> 24–138.5 h) surgery with magnetic resonance imaging-confirmed decompression in American Spinal Injury …

B Aarabi, N Akhtar-Danesh, T Chryssikos… - Journal of …, 2020 - liebertpub.com
In cervical traumatic spinal cord injury (TSCI), the therapeutic effect of timing of surgery on
neurological recovery remains uncertain. Additionally, the relationship between extent of …

[HTML][HTML] Targeted perfusion therapy in spinal cord trauma

S Saadoun, MC Papadopoulos - Neurotherapeutics, 2020 - Elsevier
We review state-of-the-art monitoring techniques for acute, severe traumatic spinal cord
injury (TSCI) to facilitate targeted perfusion of the injured cord rather than applying universal …

Efficacy of early (≤ 24 hours), Late (25–72 hours), and Delayed (> 72 hours) surgery with magnetic resonance imaging-confirmed decompression in American spinal …

B Aarabi, N Akhtar-Danesh, JM Simard… - Journal of …, 2021 - liebertpub.com
The therapeutic significance of timing of decompression in acute traumatic central cord
syndrome (ATCCS) caused by spinal stenosis remains unsettled. We retrospectively …

Early versus late surgical decompression for traumatic spinal cord injury on neurological recovery: a systematic review and meta-analysis

YL Hsieh, J Tay, SH Hsu, WT Chen, YD Fang… - Journal of …, 2021 - liebertpub.com
This study aimed to investigate whether early surgical decompression was associated with
favorable neurological recovery in patients with traumatic spinal cord injury (tSCI). We …