Generative artificial intelligence in drug discovery: basic framework, recent advances, challenges, and opportunities

A Gangwal, A Ansari, I Ahmad, AK Azad… - Frontiers in …, 2024 - frontiersin.org
There are two main ways to discover or design small drug molecules. The first involves fine-
tuning existing molecules or commercially successful drugs through quantitative structure …

Drug screening for hepatitis A virus (HAV): nicotinamide inhibits c-jun expression and hav replication

R Sasaki-Tanaka, R Masuzaki, H Okamoto… - Journal of …, 2023 - Am Soc Microbiol
Hepatitis A virus (HAV) infection often causes acute hepatitis, which results in a case fatality
rate of 0.2% and fulminant hepatitis in 0.5% of cases. However, no specific potent anti-HAV …

Artificial intelligence-assisted drug repurposing via “chemical-induced gene expression ranking”

T Masuda, K Mimori - Patterns, 2022 - cell.com
Drug repurposing using artificial intelligence algorithms is a powerful technique that
leverages existing datasets to find new medical applications for approved drugs. Pham et al …

Molecular Mechanism of Chronic Viral and Non-Viral Liver Diseases

T Kanda - International Journal of Molecular Sciences, 2023 - mdpi.com
In this Special Issue,“Molecular Mechanism of Chronic Viral and Non-viral Liver Diseases”,
invaluable articles have been published. Alcohol-associated liver disease (ALD) is one of …