Modelling autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) using mice and zebrafish

G Dougnon, H Matsui - International journal of molecular sciences, 2022 - mdpi.com
Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are two
debilitating neurodevelopmental disorders. The former is associated with social impairments …

[HTML][HTML] ADSCs-derived extracellular vesicles alleviate neuronal damage, promote neurogenesis and rescue memory loss in mice with Alzheimer's disease

X Ma, M Huang, M Zheng, C Dai, Q Song… - Journal of Controlled …, 2020 - Elsevier
Despite the various mechanisms that involved in the pathogenesis of Alzheimer's disease
(AD), neuronal damage and synaptic dysfunction are the key events leading to cognition …

[HTML][HTML] Molecular mechanisms for targeted ASD treatments

B Basilico, J Morandell, G Novarino - Current opinion in genetics & …, 2020 - Elsevier
The possibility to generate construct valid animal models enabled the development and
testing of therapeutic strategies targeting the core features of autism spectrum disorders …

NEXMIF encephalopathy: an X-linked disorder with male and female phenotypic patterns

H Stamberger, TB Hammer, E Gardella… - Genetics in …, 2021 - nature.com
Purpose Pathogenic variants in the X-linked gene NEXMIF (previously KIAA2022) are
associated with intellectual disability (ID), autism spectrum disorder, and epilepsy. We aimed …

Arsenic exposure via drinking water during pregnancy and lactation induces autism-like behaviors in male offspring mice

X Zhang, D Mei, Y Li, M You, D Wang, D Yao, Y Xu… - Chemosphere, 2022 - Elsevier
Exposure to arsenic (As), an environmental toxicant, causes damages to the central nervous
system (CNS) structure and function. Emerging epidemiological studies support that …

CSMD3 deficiency leads to motor impairments and autism-like behaviors via dysfunction of cerebellar purkinje cells in mice

K Xi, SQ Cai, HF Yan, Y Tian, J Cai… - Journal of …, 2023 - Soc Neuroscience
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with highly heritable
heterogeneity. Mutations of CUB and sushi multiple domains 3 (CSMD3) gene have been …

NEXMIF variants are associated with epilepsy with or without intellectual disability

ZL Ye, HJ Yan, QH Guo, SQ Zhang, S Luo… - … : European Journal of …, 2024 - Elsevier
Objectives Variants in NEXMIF had been reported associated with intellectual disability (ID)
without epilepsy or developmental epileptic encephalopathy (DEE). It is unkown whether …

Sex-dependent social and repetitive behavior and neurochemical profile in mouse model of autism spectrum disorder

H Ferreira, AC Sousa, J Sereno, J Martins… - Metabolites, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficits
in social interaction, impaired communication, and repetitive behaviors. ASD presents a 3: 1 …

Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice

W Zhang, J Huang, F Gao, Q You, L Ding, J Gong… - …, 2022 - thelancet.com
Background Autism spectrum disorder (ASD) is a common neurodevelopmental disease,
characterized by deficits in social communication, restricted and repetitive behaviours, and …

The GluN2B-Trp373 NMDA receptor variant is associated with autism-, epilepsy-related phenotypes and reduces NMDA receptor currents in rats

X Wang, Z Guo, D Mei, Y Zhang, S Zhao, S Hu… - Neurochemical …, 2022 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core clinical
features of abnormal communication, social interactions, atypical intelligence, and a higher …