Mitochondrial function and redox state in mammalian embryos

R Dumollard, J Carroll, MR Duchen, K Campbell… - Seminars in cell & …, 2009 - Elsevier
Mitochondria play a central and multifaceted role in the mammalian egg and early embryo,
contributing to many different aspects of early development. While the contribution of …

Animal oocyte and embryo cryopreservation

RM Pereira, CC Marques - Cell and tissue banking, 2008 - Springer
Cryopreservation of oocytes and embryos is a crucial step for the widespread and
conservation of animal genetic resources. However, oocytes and early embryos are very …

The effects of resveratrol on porcine oocyte in vitro maturation and subsequent embryonic development after parthenogenetic activation and in vitro fertilization

SS Kwak, SA Cheong, Y Jeon, E Lee, KC Choi… - Theriogenology, 2012 - Elsevier
We investigated the effects of resveratrol, a phytoalexin with various pharmacologic
activities, on in vitro maturation (IVM) of porcine oocytes. We investigated intracellular …

Differences in the incidence of apoptosis between in vivo and in vitro produced blastocysts of farm animal species: a comparative study

FJR Pomar, KJ Teerds, A Kidson, B Colenbrander… - Theriogenology, 2005 - Elsevier
The occurrence of pregnancies and births after embryo transfer (ET) of in vivo produced
embryos is generally more successful compared to that of embryos produced in vitro. This …

Anthocyanin stimulates in vitro development of cloned pig embryos by increasing the intracellular glutathione level and inhibiting reactive oxygen species

J You, J Kim, J Lim, E Lee - Theriogenology, 2010 - Elsevier
The objective was to examine the nuclear maturation of oocytes, embryonic development
after parthenogenetic activation (PA) and somatic cell nuclear transfer (SCNT), and gene …

Vitamin D deficiency: infertility and neurodevelopmental diseases (attention deficit hyperactivity disorder, autism, and schizophrenia)

MJ Berridge - American Journal of Physiology-Cell …, 2018 - journals.physiology.org
The process of development depends on a number of signaling systems that regulates the
progressive sequence of developmental events. Infertility and neurodevelopmental …

Enrichment of in vitro maturation medium for buffalo (Bubalus bubalis) oocytes with thiol compounds: effects of cystine on glutathione synthesis and embryo …

B Gasparrini, L Boccia, J Marchandise, R Di Palo… - Theriogenology, 2006 - Elsevier
The purpose of this study was to evaluate whether enriching the oocyte in vitro maturation
medium with cystine, in the presence of cysteamine, would improve the in vitro embryo …

Reactive oxygen species: a double-edged sword in reproduction

F Silva, A Marques, A Chaveiro - The Open Veterinary Science …, 2010 - benthamopen.com
Antioxidants are compounds that protect cells against the damaging effects of reactive
oxygen species (ROS) such as singlet oxygen, superoxide, peroxyl radicals, hydroxyl …

Improving the cytoplasmic maturation of bovine oocytes matured in vitro with intracellular and/or extracellular antioxidants is not associated with increased rates of …

NAS Rocha-Frigoni, BCS Leão, PC Dall'Acqua… - Theriogenology, 2016 - Elsevier
The production of reactive oxygen species (ROS) is a normal process that occurs in the
cellular mitochondrial respiratory chain. However, an increase in ROS levels during in vitro …

Where ferroptosis inhibitors and paraquat detoxification mechanisms intersect, exploring possible treatment strategies

N Rashidipour, S Karami-Mohajeri, A Mandegary… - Toxicology, 2020 - Elsevier
Paraquat (PQ) is a fast-acting and effective herbicide that is used throughout the world to
eliminate weeds. Over the past years, PQ was considered one of the most popular poisoning …