Background Smoking is a known lung cancer cause, but no detailed quantitative systematic
review exists. We summarize evidence for various indices. Methods Papers published …

EPIC is among the largest cohort studies, with approximately 475,000 study participants, on
the etiological influence of diet and chronic diseases. During a 4-year recruitment period …

Deep learning (DL) can accelerate the prediction of prognostic biomarkers from routine
pathology slides in colorectal cancer (CRC). However, current approaches rely on …

Background & Aims Microsatellite instability (MSI) and mismatch-repair deficiency (dMMR)
in colorectal tumors are used to select treatment for patients. Deep learning can detect MSI …

Abstract The LifeLines Cohort Study is a large population-based cohort study and biobank
that was established as a resource for research on complex interactions between …

Background Microsatellite instability (MSI)/mismatch repair deficiency (dMMR) is a key
genetic feature which should be tested in every patient with colorectal cancer (CRC) …

Background Long-term exposure to participate matter air pollution has been associated with
increased cardiopulmonary mortality in the USA. We aimed to assess the relation between …

Background Several studies have found an effect on mortality of between-city contrasts in
long-term exposure to air pollution. The effect of within-city contrasts is still poorly …

The case-cohort design is most useful in analyzing time to failure in a large cohort in which
failure is rare. Covariate information is collected from all failures and a representative …

Both carcinogenic and anticarcinogenic properties have been reported for the synthetic
antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). The …