Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Role of silymarin in cancer treatment: facts, hypotheses, and questions

T Koltai, L Fliegel - Journal of Evidence-Based Integrative …, 2022 - journals.sagepub.com
The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

Silymarin and cancer: A dual strategy in both in chemoprevention and chemosensitivity

D Delmas, J Xiao, A Vejux, V Aires - Molecules, 2020 - mdpi.com
Silymarin extracted from milk thistle consisting of flavonolignan silybin has shown
chemopreventive and chemosensitizing activity against various cancers. The present review …

Effects and mechanisms of dietary bioactive compounds on breast cancer prevention

K Ganesan, B Du, J Chen - Pharmacological Research, 2022 - Elsevier
Breast cancer (BC) is the most often diagnosed cancer among females globally and has
become an increasing global health issue over the last decades. Despite the substantial …

Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator

Z Jahanafrooz, N Motamed, B Rinner, A Mokhtarzadeh… - Life sciences, 2018 - Elsevier
Silibinin is a natural plant polyphenol with high antioxidant and anticancer properties, which
causes broad-spectrum efficacy against cancer, including cell cycle arrest and apoptosis in …

Mechanistic evaluation of phytochemicals in breast cancer remedy: current understanding and future perspectives

M Younas, C Hano, N Giglioli-Guivarc'h, BH Abbasi - RSC advances, 2018 - pubs.rsc.org
Breast cancer is one of the most commonly diagnosed cancers around the globe and
accounts for a large proportion of fatalities in women. Despite the advancement in …

Polyphenols as promising drugs against main breast cancer signatures

M Losada-Echeberría, M Herranz-López, V Micol… - Antioxidants, 2017 - mdpi.com
Breast cancer is one of the most common neoplasms worldwide, and in spite of clinical and
pharmacological advances, it is still a clinical problem, causing morbidity and mortality. On …

Phytochemicals based chemopreventive and chemotherapeutic strategies and modern technologies to overcome limitations for better clinical applications

VK Singh, D Arora, MI Ansari… - Phytotherapy …, 2019 - Wiley Online Library
Naturally occurring phytochemicals or plant derivatives are now being explored extensively
for their health's benefits and medicinal uses. The therapeutic effect of phytochemicals has …

Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase …

AG Ribeiro, SMV de Almeida, JF de Oliveira… - European Journal of …, 2019 - Elsevier
Abstract Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were
synthetized and their biological properties were investigated, among which, the ability to …

Role of plant-derived flavonoids in cancer treatment

P Tiwari, KP Mishra - Nutrition and Cancer, 2023 - Taylor & Francis
Flavonoids are polyphenolic phytochemicals, which occur naturally in plants and possess
both anti-oxidant and pro-oxidant properties. Flavonoids are gaining increasing popularity in …