Increasing confidence of allele calls with molecular counting

J Casbon, S Brenner, R Osborne… - US Patent …, 2013 - Google Patents
Aspects of the present invention include methods and com positions for determining the
number of individual poly nucleotide molecules originating from the same genomic region of …

Methods for making nucleotide probes for sequencing and synthesis

GM Church, K Zhang, J Chou - US Patent 8,771,950, 2014 - Google Patents
Compositions and methods for making a plurality of probes for analyzing a plurality of
nucleic acid samples are provided. Compositions and methods for analyzing a plurality of …

Single cell bar-coding for antibody discovery

F Vigneault, AW BRIGGS - US Patent 9,816,088, 2017 - Google Patents
G01N33/5008—Chemical analysis of biological material, eg blood, urine; Testing involving
biospecific ligand binding methods; Immunological testing involving human or animal cells …

Methods, systems, and computer readable media for nucleic acid sequencing

M Davey, S Cawley, A Williams - US Patent 10,241,075, 2019 - Google Patents
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Single molecule amplification and detection of DNA length

M Knapp, J Baker, A Chow, A Kopf-Sill… - US Patent App. 10 …, 2005 - Google Patents
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Patents US20050042639A1 - Single molecule amplification and detection of DNA length …

Oligonucleotides for genotyping thymidylate synthase gene

H Yasuno, K Mori - US Patent 7,919,235, 2011 - Google Patents
Oligonucleotides for genotyping the thymidylate synthase gene are provided. The number of
tandem repeats in the promoter region of the thymidylate synthase gene can be identified …

Nanogrid rolling circle DNA sequencing

GM Church, GJ Porreca, J Shendure… - US Patent …, 2017 - Google Patents
The present invention relates to methods for sequencing a polynucleotide immobilized on
an array having a plurality of specific regions each having a defined diameter size, including …

Method and apparatus for generating thermal melting curves in a microfluidic device

SA Sundberg, MR Knapp, IT Knight, DJ Boles… - US Patent …, 2014 - Google Patents
(54) METHOD AND APPARATUS FOR(52) US Cl. GENERATING THERMAL MELTING
CPC.............. CI2O I/6844 (2013.01); C12O I/686 CURVES IN AMCROFLUIDIC …

Thermal cycling system

G Maltezos, M Johnston, D Goodwin, A Scherer… - US Patent …, 2012 - Google Patents
Int. Cl.(51) y2M I/00(2006.01) This invention provides a system for performing PCR, and
CI2P 19/34(2006.015 real time PCR in particular with great speed and specificity.(52) US Cl …

Systems and methods for fluorescence detection with a movable detection module

I Kordunsky, JA Goldman, MJ Finney - US Patent 7,148,043, 2006 - Google Patents
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