New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase

MA Sirover - Biochimica et Biophysica Acta (BBA)-Protein Structure …, 1999 - Elsevier
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was considered a classical
glycolytic protein examined for its pivotal role in energy production. It was also used as a …

Skeletal muscle mass and composition during mammalian hibernation

CJ Cotton - Journal of Experimental Biology, 2016 - journals.biologists.com
Hibernation is characterized by prolonged periods of inactivity with concomitantly low
nutrient intake, conditions that would typically result in muscle atrophy combined with a loss …

Metabolic reprogramming involving glycolysis in the hibernating brown bear skeletal muscle

B Chazarin, KB Storey, A Ziemianin, S Chanon… - Frontiers in …, 2019 - Springer
Background In mammals, the hibernating state is characterized by biochemical adjustments,
which include metabolic rate depression and a shift in the primary fuel oxidized from …

Expression, purification, and characterization of recombinant nonphosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Clostridium …

A Iddar, F Valverde, A Serrano, A Soukri - Protein Expression and …, 2002 - Elsevier
Clostridium acetobutylicum gapN was cloned and expressed in Escherichia coli BL-21. The
IPTG-induced nonphosphorylating NADP-dependent GAPDH (GAPN) has been purified …

Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders

MD Berry - Journal of Psychiatry and Neuroscience, 2004 - jpn.ca
Recent articles have highlighted numerous additional functions of glyceraldehyde-3-
phosphate dehydrogenase (GAPDH) that are independent of its well-documented glycolytic …

Corynebacterium glutamicum Glyceraldehyde-3-Phosphate Dehydrogenase Isoforms with Opposite, ATP-Dependent Regulation

CA Omumasaba, N Okai, M Inui… - Journal of Molecular …, 2004 - karger.com
Corynebacterium glutamicum gapA and gapB encode glyceraldehyde-3-phosphate
dehydrogenases (GAPDHs) that differ in molecular weight and activity in the presence of …

[HTML][HTML] Mechanisms and Countermeasures for Muscle Atrophy in Microgravity

Y Liu, X Cao, Q Zhou, C Deng, Y Yang, D Huang… - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Previous studies have revealed that muscle atrophy emerges as a significant challenge
faced by astronauts during prolonged missions in space. A loss in muscle mass results in a …

Occurrence of a differential expression of the glyceraldehyde-3-phosphate dehydrogenase gene in muscle and liver from euthermic and induced hibernating jerboa …

A Soukri, F Valverde, N Hafid, MS Elkebbaj, A Serrano - Gene, 1996 - Elsevier
A cDNA clone which contains the near-complete open reading frame (ORF) encoding
glyceraldehyde-3-phosphate dehydrogenase (GAPDH, EC 1.2. 1.12) was obtained by …

Purification of recombinant non-phosphorylating NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Streptococcus pyogenes expressed in E. coli

A Iddar, F Valverde, A Serrano, A Soukri - Molecular and cellular …, 2003 - Springer
Streptococcus pyogenes gap N was cloned and expressed by functional complementation
of the Escherichia gap mutant W3CG. The IPTG-induced NADP non-phosphorylating …

In vitro effect of metal ions on the activity of two amphibian glyceraldehyde-3-phosphate dehydrogenases: potential metal binding sites

K Mounaji, M Vlassi, NE Erraiss, M Wegnez… - … and Physiology Part B …, 2003 - Elsevier
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH, EC 1.2. 1.12) was purified from two
amphibian species, Xenopus laevis and Pleurodeles waltl. Comparative studies revealed …