Acanthamoeba Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs

B Shing, M Balen, JH McKerrow… - Expert review of anti …, 2021 - Taylor & Francis
Introduction: Acanthamoeba encompasses several species of free-living ameba
encountered commonly throughout the environment. Unfortunately, these species of ameba …

Synthesis of iridium and ruthenium complexes with (N, N),(N, O) and (O, O) coordinating bidentate ligands as potential anti-cancer agents

SJ Lucas, RM Lord, RL Wilson, RM Phillips… - Dalton …, 2012 - pubs.rsc.org
Several Ru-arene and Ir–Cp* complexes have been prepared incorporating (N, N),(N, O)
and (O, O) coordinating bidentate ligands and have been found to be active against both HT …

Quinoid systems in chemistry and pharmacology

J López, F De La Cruz, Y Alcaraz, F Delgado… - Medicinal Chemistry …, 2015 - Springer
In this paper, we present a brief review of quinoid systems, focusing on their chemical
synthesis over the last decade. We address not only major methods of synthesizing …

Cobalt nanoparticles as novel nanotherapeutics against Acanthamoeba castellanii

A Anwar, A Numan, R Siddiqui, M Khalid, NA Khan - Parasites & vectors, 2019 - Springer
Abstract Background Species of Acanthamoeba are facultative pathogens which can cause
sight threatening Acanthamoeba keratitis and a rare but deadly brain infection …

Metal complexes of 'Heena'(2-hydroxy-1, 4-naphthoquinone): Synthesis, Characterization and anticancer activity

N Mone, S Harihar, S Salunke-Gawali, S Satpute… - Inorganica Chimica …, 2023 - Elsevier
Abstract The Mn (II), Co (II), Ni (II), Cu (II) and Zn (II) complexes of Henna; 2-hydroxy-1, 4-
naphthoquinone (Lw) are synthesized at 0° C (Mn 2+; 1, Co 2+; 2, Ni 2+; 3, Cu 2+; 4 and Zn …

HS‐SPME coupled with GC–MS for elucidating differences between the volatile components in wild and cultivated Atractylodes chinensis

H Lei, J Yue, X Yin, W Fan, S Tan, L Qin… - Phytochemical …, 2023 - Wiley Online Library
Introduction Atractylodes chinensis is a Chinese herb that is used in traditional medicine; it
contains volatile components that have enormous potential for pharmaceutical, food, and …

Synthesis and cytotoxic activity of metallic complexes of lawsone

S Oramas-Royo, C Torrejon, I Cuadrado… - Bioorganic & medicinal …, 2013 - Elsevier
In the present study, a series of metallic complexes of the 1, 4-naphthoquinone lawsone (2–
6) were synthesized and evaluated for potential cytotoxicity in a mouse leukemic …

Effects of Shape and Size of Cobalt Phosphate Nanoparticles against Acanthamoeba castellanii

A Anwar, L Chi Fung, A Anwar, P Jagadish, A Numan… - Pathogens, 2019 - mdpi.com
T4 genotype Acanthamoeba are opportunistic pathogens that cause two types of infections,
including vision-threatening Acanthamoeba keratitis (AK) and a fatal brain infection known …

Anti-Acanthamoebic properties of resveratrol and demethoxycurcumin

Y Aqeel, J Iqbal, R Siddiqui, AH Gilani… - Experimental …, 2012 - Elsevier
Acanthamoeba is an opportunist protist pathogen that is known to infect the cornea to
produce eye keratitis and the central nervous system to produce fatal granulomatous …

Inhibition of 3-hydroxy-3-methylglutaryl–coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections

CM Martín-Navarro, J Lorenzo-Morales… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Acanthamoeba is an opportunistic pathogen in humans, whose infections most commonly
manifest as Acanthamoeba keratitis or, more rarely, granulomatous amoebic encephalitis …