Treatment after progression in the era of immunotherapy

S Billan, O Kaidar-Person, Z Gil - The Lancet Oncology, 2020 - thelancet.com
Immunotherapy represents a paradigm shift in oncology treatment. The goal of
immunotherapy is to overcome immunosuppression induced by a tumour and its …

Regulation of cancer‐immunity cycle and tumor microenvironment by nanobiomaterials to enhance tumor immunotherapy

J Yang, C Zhang - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
In the past decade, we have witnessed the revolution in cancer therapy, especially in the
rapid development of cancer immunotherapy. In particular, the introduction of nanomedicine …

Improved efficacy of ramucirumab plus docetaxel after nivolumab failure in previously treated non‐small cell lung cancer patients

A Shiono, K Kaira, A Mouri, O Yamaguchi… - Thoracic …, 2019 - Wiley Online Library
Background It is unclear whether the chemotherapy response improves after exposure to
immunotherapy. Antiangiogenic agents have been shown to stimulate the immune system …

[HTML][HTML] Improved efficacy of taxanes and ramucirumab combination chemotherapy after exposure to anti-PD-1 therapy in advanced gastric cancer

A Sasaki, A Kawazoe, T Eto, M Okunaka, S Mishima… - ESMO …, 2020 - ncbi.nlm.nih.gov
Background The efficacy and safety of chemotherapy (CTx) after anti-PD-1 therapy in
patients with advanced gastric cancer (AGC) remains unclear. Methods Medical records of …

Safety and efficacy of cetuximab-based salvage chemotherapy after checkpoint inhibitors in head and neck cancer

S Cabezas-Camarero, MN Cabrera-Martín… - The …, 2021 - academic.oup.com
Background There are still few data on the activity and safety of cetuximab-based salvage
chemotherapy after immunotherapy (SCAI) in patients with squamous cell cancer of the …

Randomised phase II trial of trifluridine/tipiracil (FTD/TPI) plus ramucirumab (RAM) versus trifluridine/tipiracil for previously treated patients with advanced gastric or …

N Takahashi, H Hara, K Nagashima, K Hirata… - BMC cancer, 2023 - Springer
Abstract Background Trifluridine/tipiracil (FTD/TPI) prolongs survival in the third-or later-line
treatment for advanced gastric cancer (GC), esophagogastric junction (EGJ) …

Outcomes on anti‐VEGFR‐2/paclitaxel treatment after progression on immune checkpoint inhibition in patients with metastatic gastroesophageal adenocarcinoma

LA Kankeu Fonkoua, S Chakrabarti… - … journal of cancer, 2021 - Wiley Online Library
Through our involvement in KEYNOTE‐059, we unexpectedly observed durable responses
in two patients with metastatic gastroesophageal adenocarcinoma (mGEA) who received …

Novel implications of MicroRNAs, long non-coding RNAs and circular RNAs in drug resistance of esophageal cancer

L Wei, J Sun, N Zhang, Y Shen, T Wang, Z Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Esophageal cancer is the eighth most common malignancy and the sixth leading cause of
cancer-related deaths worldwide. Chemotherapy based on platinum drugs, 5-fluorouracil …

Cholangiocarcinoma, sequential chemotherapy, and prognostic tests

HW Bruckner, R De Jager, E Knopf… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction Routine blood tests are prognostic tests for patients with cholangiocarcinoma.
New drug regimens may produce a median overall survival of 2 years or more. Methods This …

Actionable tests and treatments for patients with gastrointestinal cancers and historically short median survival times

HW Bruckner, F Bassali, E Dusowitz, D Gurell, A Book… - Plos one, 2022 - journals.plos.org
Background Patients have difficult unmet needs when standard chemotherapy produces a
median survival of less than 1 year or many patients will experience severe toxicities. Blood …